Squalamine reverses age-associated changes of firing patterns of myenteric sensory neurons and vagal fibres

Squalamine reverses age-associated changes of firing patterns of myenteric sensory neurons and vagal fibres

Abstract Vagus nerve signaling is a key component of the gut-brain axis and regulates diverse physiological processes that decline with age. Gut to brain vagus firing patterns are regulated by myenteric intrinsic primary afferent neuron (IPAN) to vagus neurotransmission. It remains unclear how IPANs...

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Bibliographic Details
Main Authors: Karen-Anne McVey Neufeld, Yu-Kang Mao, Christine L. West, Matthew Ahn, Hashim Hameed, Eiko Iwashita, Andrew M. Stanisz, Paul Forsythe, Denise Barbut, Michael Zasloff, Wolfgang A. Kunze
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05623-2

Internet

https://doi.org/10.1038/s42003-023-05623-2

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