1000 human genomes carry widespread signatures of GC biased gene conversion
Abstract Background GC-Biased Gene Conversion (gBGC) is one of the important theories put forward to explain profound long-range non-randomness in nucleotide compositions along mammalian chromosomes. Nucleotide changes due to gBGC are hard to distinguish from regular mutations. Here, we present an a...
Main Authors: | Rajib Dutta, Arnab Saha-Mandal, Xi Cheng, Shuhao Qiu, Jasmine Serpen, Larisa Fedorova, Alexei Fedorov |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2018-04-01
|
Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-018-4593-1 |
Similar Items
-
THE SNP-MED SYSTEM FOR ANALYSIS OF THE EFFECT OF SINGLE-NUCLEOTIDE POLYMORPHISMS ON THE FUNCTION OF GENES ASSOCIATED WITH SOCIALLY SIGNIFICANT DISEASES
by: N. L. Podkolodnyy, et al.
Published: (2015-01-01) -
Profound Non-Randomness in Dinucleotide Arrangements within Ultra-Conserved Non-Coding Elements and the Human Genome
by: Larisa Fedorova, et al.
Published: (2023-08-01) -
Nucleotide Composition of Ultra-Conserved Elements Shows Excess of GpC and Depletion of GG and CC Dinucleotides
by: Larisa Fedorova, et al.
Published: (2022-11-01) -
LD-annot: A Bioinformatics Tool to Automatically Provide Candidate SNPs With Annotations for Genetically Linked Genes
by: Julien Prunier, et al.
Published: (2019-11-01) -
Identification of the SIRT1 gene's most harmful non-synonymous SNPs and their effects on functional and structural features-an in silico analysis [version 2; peer review: 2 approved]
by: Desy Thayyil Menambath, et al.
Published: (2024-01-01)