NATRIUM DIKLOFENAK UNTUK PENGOBATAN NOKTURIA YANG DISEBABKAN OLEH NOCTURNAL POLYURIA
Objective: To investigate the efficacy of diclofenac 50 mg (Non-Steroidal Anti-Inflammatory Drug) in the treatment of nocturnal polyuria. Materials and methods: Twenty four patients (23 male and 1 female) with a mean age of 61 years (range 34 – 80) diagnosed with nocturnal polyuria were recruited. T...
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| Format: | Article |
| Language: | English |
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IKATAN AHLI UROLOGI INDONESIA
2014-09-01
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| Series: | Jurnal Urologi Indonesia |
| Subjects: | |
| Online Access: | http://juri.urologi.or.id/juri/article/view/358 |
| _version_ | 1818208976743956480 |
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| author | Eddy Sunarno Sabilal Alif Sunaryo Hardjowijoto Widodo J P |
| author_facet | Eddy Sunarno Sabilal Alif Sunaryo Hardjowijoto Widodo J P |
| author_sort | Eddy Sunarno |
| collection | DOAJ |
| description | Objective: To investigate the efficacy of diclofenac 50 mg (Non-Steroidal Anti-Inflammatory Drug) in the treatment of nocturnal polyuria. Materials and methods: Twenty four patients (23 male and 1 female) with a mean age of 61 years (range 34 – 80) diagnosed with nocturnal polyuria were recruited. The study period comprised 2 weeks of either placebo or active medication. Following one-week rest period, patients were crossed over to the other medication for a further 2 weeks. Frequency volume charts were completed during the second week of each of the two study periods along with feedback forms to assess any subjective improvement in symptoms during each of the study periods. Results: A significant improvement in the symptoms was noted for diclofenac when compared with the placebo. The mean nocturnal frequency decreased from 3,61 ± 2,45 to 2,39 ± 1,1 (p<0,05) and the mean 24 h urine volume decreased from 1139,64 ± 365 to 1089 ± 324 (p>0,05), but there is no statistically different. No significant side effects were reported. Conclusion: Natrium diclofenac 50 mg are effective in the treatment of nocturnal polyuria causing a decrease in nocturnal frequency with subjective symptom improvement. Our study suggests, Natrium diclofenac not to prolonged treatment. Further research to find the alternative treatment is recommended. |
| first_indexed | 2024-12-12T04:53:22Z |
| format | Article |
| id | doaj.art-8c5dc05bf00447b7be30147992400043 |
| institution | Directory Open Access Journal |
| issn | 0853-442X 2355-1402 |
| language | English |
| last_indexed | 2024-12-12T04:53:22Z |
| publishDate | 2014-09-01 |
| publisher | IKATAN AHLI UROLOGI INDONESIA |
| record_format | Article |
| series | Jurnal Urologi Indonesia |
| spelling | doaj.art-8c5dc05bf00447b7be301479924000432022-12-22T00:37:25ZengIKATAN AHLI UROLOGI INDONESIAJurnal Urologi Indonesia0853-442X2355-14022014-09-0116110.32421/juri.v16i1.358358NATRIUM DIKLOFENAK UNTUK PENGOBATAN NOKTURIA YANG DISEBABKAN OLEH NOCTURNAL POLYURIAEddy Sunarno0Sabilal Alif1Sunaryo Hardjowijoto2Widodo J P3Departemen/SMF Urologi, FK Universitas Airlangga/RSU Dr. Soetomo, SurabayaDepartemen/SMF Urologi, FK Universitas Airlangga/RSU Dr. Soetomo, SurabayaDepartemen/SMF Urologi, FK Universitas Airlangga/RSU Dr. Soetomo, SurabayaFakultas Kesehatan Masyarakat, FK Universitas Airlangga/RSU Dr. Soetomo, SurabayaObjective: To investigate the efficacy of diclofenac 50 mg (Non-Steroidal Anti-Inflammatory Drug) in the treatment of nocturnal polyuria. Materials and methods: Twenty four patients (23 male and 1 female) with a mean age of 61 years (range 34 – 80) diagnosed with nocturnal polyuria were recruited. The study period comprised 2 weeks of either placebo or active medication. Following one-week rest period, patients were crossed over to the other medication for a further 2 weeks. Frequency volume charts were completed during the second week of each of the two study periods along with feedback forms to assess any subjective improvement in symptoms during each of the study periods. Results: A significant improvement in the symptoms was noted for diclofenac when compared with the placebo. The mean nocturnal frequency decreased from 3,61 ± 2,45 to 2,39 ± 1,1 (p<0,05) and the mean 24 h urine volume decreased from 1139,64 ± 365 to 1089 ± 324 (p>0,05), but there is no statistically different. No significant side effects were reported. Conclusion: Natrium diclofenac 50 mg are effective in the treatment of nocturnal polyuria causing a decrease in nocturnal frequency with subjective symptom improvement. Our study suggests, Natrium diclofenac not to prolonged treatment. Further research to find the alternative treatment is recommended.http://juri.urologi.or.id/juri/article/view/358Natrium diclofenacnocturia |
| spellingShingle | Eddy Sunarno Sabilal Alif Sunaryo Hardjowijoto Widodo J P NATRIUM DIKLOFENAK UNTUK PENGOBATAN NOKTURIA YANG DISEBABKAN OLEH NOCTURNAL POLYURIA Jurnal Urologi Indonesia Natrium diclofenac nocturia |
| title | NATRIUM DIKLOFENAK UNTUK PENGOBATAN NOKTURIA YANG DISEBABKAN OLEH NOCTURNAL POLYURIA |
| title_full | NATRIUM DIKLOFENAK UNTUK PENGOBATAN NOKTURIA YANG DISEBABKAN OLEH NOCTURNAL POLYURIA |
| title_fullStr | NATRIUM DIKLOFENAK UNTUK PENGOBATAN NOKTURIA YANG DISEBABKAN OLEH NOCTURNAL POLYURIA |
| title_full_unstemmed | NATRIUM DIKLOFENAK UNTUK PENGOBATAN NOKTURIA YANG DISEBABKAN OLEH NOCTURNAL POLYURIA |
| title_short | NATRIUM DIKLOFENAK UNTUK PENGOBATAN NOKTURIA YANG DISEBABKAN OLEH NOCTURNAL POLYURIA |
| title_sort | natrium diklofenak untuk pengobatan nokturia yang disebabkan oleh nocturnal polyuria |
| topic | Natrium diclofenac nocturia |
| url | http://juri.urologi.or.id/juri/article/view/358 |
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