Clinical Application and Educational Training for Pharmacogenomics
Pharmacogenomics—defined as the study of how genes affect a person’s response to drugs—is growing in importance for clinical care. Many medications have evidence and drug labeling related to pharmacogenomics and patient care. New evidence supports the use of pharmacogenomics in clinical settings, an...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-09-01
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| Series: | Pharmacy |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2226-4787/8/3/163 |
| _version_ | 1827706960508616704 |
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| author | Jason W. Guy Isha Patel Julie H. Oestreich |
| author_facet | Jason W. Guy Isha Patel Julie H. Oestreich |
| author_sort | Jason W. Guy |
| collection | DOAJ |
| description | Pharmacogenomics—defined as the study of how genes affect a person’s response to drugs—is growing in importance for clinical care. Many medications have evidence and drug labeling related to pharmacogenomics and patient care. New evidence supports the use of pharmacogenomics in clinical settings, and genetic testing may optimize medication selection and dosing. Despite these advantages, the integration of pharmacogenomics into clinical decisions remains variable and challenging in certain practice settings. To ensure consistent application across settings, sufficient education amongst current and future healthcare providers is necessary to further integrate pharmacogenomics into routine clinical practice. This review highlights current evidence supporting clinical application of medications with pharmacogenomic labeling. The secondary objective is to review current strategies for educating health professionals and student trainees. One national organization predicts that most regions in the United States will soon contain at least one healthcare system capable of applying pharmacogenomic information. Applying genotype-guided dosing to several FDA-approved medications may help produce beneficial changes in patient outcomes. Identifying best practices for educating health care professionals and trainees remains vitally important for continuing growth of pharmacogenomic services. As pharmacogenomics continues to expand into more areas of healthcare, current and future practitioners must pursue and maintain competence in pharmacogenomics to ensure better outcomes for patients. |
| first_indexed | 2024-03-10T16:36:00Z |
| format | Article |
| id | doaj.art-8c5f65b9b7b24328807a6cb97328d926 |
| institution | Directory Open Access Journal |
| issn | 2226-4787 |
| language | English |
| last_indexed | 2024-03-10T16:36:00Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmacy |
| spelling | doaj.art-8c5f65b9b7b24328807a6cb97328d9262023-11-20T12:25:40ZengMDPI AGPharmacy2226-47872020-09-018316310.3390/pharmacy8030163Clinical Application and Educational Training for PharmacogenomicsJason W. Guy0Isha Patel1Julie H. Oestreich2Department of Pharmacy Practice, College of Pharmacy, University of Findlay, Findlay, OH 45840, USADepartment of Pharmacy Practice, Administration and Research, Marshall University School of Pharmacy, Huntington, WV 25755, USADepartment of Pharmaceutical Sciences, College of Pharmacy, University of Findlay, Findlay, OH 45840, USAPharmacogenomics—defined as the study of how genes affect a person’s response to drugs—is growing in importance for clinical care. Many medications have evidence and drug labeling related to pharmacogenomics and patient care. New evidence supports the use of pharmacogenomics in clinical settings, and genetic testing may optimize medication selection and dosing. Despite these advantages, the integration of pharmacogenomics into clinical decisions remains variable and challenging in certain practice settings. To ensure consistent application across settings, sufficient education amongst current and future healthcare providers is necessary to further integrate pharmacogenomics into routine clinical practice. This review highlights current evidence supporting clinical application of medications with pharmacogenomic labeling. The secondary objective is to review current strategies for educating health professionals and student trainees. One national organization predicts that most regions in the United States will soon contain at least one healthcare system capable of applying pharmacogenomic information. Applying genotype-guided dosing to several FDA-approved medications may help produce beneficial changes in patient outcomes. Identifying best practices for educating health care professionals and trainees remains vitally important for continuing growth of pharmacogenomic services. As pharmacogenomics continues to expand into more areas of healthcare, current and future practitioners must pursue and maintain competence in pharmacogenomics to ensure better outcomes for patients.https://www.mdpi.com/2226-4787/8/3/163pharmacogenomicspharmacy educationpharmacogenomics educationclinical outcomes |
| spellingShingle | Jason W. Guy Isha Patel Julie H. Oestreich Clinical Application and Educational Training for Pharmacogenomics Pharmacy pharmacogenomics pharmacy education pharmacogenomics education clinical outcomes |
| title | Clinical Application and Educational Training for Pharmacogenomics |
| title_full | Clinical Application and Educational Training for Pharmacogenomics |
| title_fullStr | Clinical Application and Educational Training for Pharmacogenomics |
| title_full_unstemmed | Clinical Application and Educational Training for Pharmacogenomics |
| title_short | Clinical Application and Educational Training for Pharmacogenomics |
| title_sort | clinical application and educational training for pharmacogenomics |
| topic | pharmacogenomics pharmacy education pharmacogenomics education clinical outcomes |
| url | https://www.mdpi.com/2226-4787/8/3/163 |
| work_keys_str_mv | AT jasonwguy clinicalapplicationandeducationaltrainingforpharmacogenomics AT ishapatel clinicalapplicationandeducationaltrainingforpharmacogenomics AT juliehoestreich clinicalapplicationandeducationaltrainingforpharmacogenomics |