The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation.

The effect of central loops in miRNA:MRE duplexes on the efficiency of miRNA-mediated gene regulation.

MicroRNAs (miRNAs) guide posttranscriptional repression of mRNAs. Hundreds of miRNAs have been identified but the target identification of mammalian mRNAs is still a difficult task due to a poor understanding of the interaction between miRNAs and the miRNA recognizing element (MRE). In recent resear...

Full description

Bibliographic Details
Main Authors: Wenbin Ye, Qing Lv, Chung-Kwun Amy Wong, Sean Hu, Chao Fu, Zhong Hua, Guoping Cai, Guoxi Li, Burton B Yang, Yaou Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/18320040/?tool=EBI

Similar Items

Similar Items