Effects of Tolvaptan on Oxidative Stress in ADPKD: A Molecular Biological Approach

Effects of Tolvaptan on Oxidative Stress in ADPKD: A Molecular Biological Approach

Autosomal dominant polycystic disease (ADPKD) is the most frequent monogenic kidney disease. It causes progressive renal failure, endothelial dysfunction, and hypertension, all of which are strictly linked to oxidative stress (OxSt). Treatment with tolvaptan is known to slow the renal deterioration...

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Bibliographic Details
Main Authors: Matteo Rigato, Gianni Carraro, Irene Cirella, Silvia Dian, Valentina Di Vico, Lucia Federica Stefanelli, Verdiana Ravarotto, Giovanni Bertoldi, Federico Nalesso, Lorenzo A. Calò
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Journal of Clinical Medicine
Subjects:
ADPKD
oxidative stress
tolvaptan
Online Access:https://www.mdpi.com/2077-0383/11/2/402

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