The definition of pulmonary hypertension: history, practical implications and current controversies

The definition of pulmonary hypertension (PH) is based on a growing body of evidence and represents the result of ongoing discussions within the PH community over the past 50 years. In 2018, the most recent World Symposium on Pulmonary Hypertension introduced significant changes in the definition of...

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Main Authors: Gabor Kovacs, Horst Olschewski
Format: Article
Language:English
Published: European Respiratory Society 2021-09-01
Series:Breathe
Online Access:http://breathe.ersjournals.com/content/17/3/210076.full
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author Gabor Kovacs
Horst Olschewski
author_facet Gabor Kovacs
Horst Olschewski
author_sort Gabor Kovacs
collection DOAJ
description The definition of pulmonary hypertension (PH) is based on a growing body of evidence and represents the result of ongoing discussions within the PH community over the past 50 years. In 2018, the most recent World Symposium on Pulmonary Hypertension introduced significant changes in the definition of PH by lowering the mean pulmonary arterial pressure threshold to >20 mmHg and (re)introducing the pulmonary vascular resistance ≥3 WU cut-off for all forms of pre-capillary PH. These changes and their potential clinical impact have been the subject of lively discussions in the community and some important questions and controversies have been identified. In this review we aim to present the development of the definition of PH over the past decades and discuss the main arguments that led to relevant modifications. In addition, we address the practical implications of the most recent changes and controversies that still exist. Educational aims To review the historical development of the definition of pulmonary hypertension. To discuss practical implications and current controversies of the currently recommended definitions of pulmonary hypertension and pulmonary arterial hypertension.
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spelling doaj.art-8c6d383b70c34b82b3a7a230d4d1eb7c2022-12-21T20:47:39ZengEuropean Respiratory SocietyBreathe1810-68382073-47352021-09-0117310.1183/20734735.0076-20210076-2021The definition of pulmonary hypertension: history, practical implications and current controversiesGabor Kovacs0Horst Olschewski1 Dept of Internal Medicine, Division of Pulmonology, Medical University of Graz, Graz, Austria Dept of Internal Medicine, Division of Pulmonology, Medical University of Graz, Graz, Austria The definition of pulmonary hypertension (PH) is based on a growing body of evidence and represents the result of ongoing discussions within the PH community over the past 50 years. In 2018, the most recent World Symposium on Pulmonary Hypertension introduced significant changes in the definition of PH by lowering the mean pulmonary arterial pressure threshold to >20 mmHg and (re)introducing the pulmonary vascular resistance ≥3 WU cut-off for all forms of pre-capillary PH. These changes and their potential clinical impact have been the subject of lively discussions in the community and some important questions and controversies have been identified. In this review we aim to present the development of the definition of PH over the past decades and discuss the main arguments that led to relevant modifications. In addition, we address the practical implications of the most recent changes and controversies that still exist. Educational aims To review the historical development of the definition of pulmonary hypertension. To discuss practical implications and current controversies of the currently recommended definitions of pulmonary hypertension and pulmonary arterial hypertension.http://breathe.ersjournals.com/content/17/3/210076.full
spellingShingle Gabor Kovacs
Horst Olschewski
The definition of pulmonary hypertension: history, practical implications and current controversies
Breathe
title The definition of pulmonary hypertension: history, practical implications and current controversies
title_full The definition of pulmonary hypertension: history, practical implications and current controversies
title_fullStr The definition of pulmonary hypertension: history, practical implications and current controversies
title_full_unstemmed The definition of pulmonary hypertension: history, practical implications and current controversies
title_short The definition of pulmonary hypertension: history, practical implications and current controversies
title_sort definition of pulmonary hypertension history practical implications and current controversies
url http://breathe.ersjournals.com/content/17/3/210076.full
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