Insight into the PTP1B Inhibitory Activity of Arylbenzofurans: An In Vitro and In Silico Study

Insight into the PTP1B Inhibitory Activity of Arylbenzofurans: An In Vitro and In Silico Study

Protein tyrosine phosphatase 1B (PTP1B) plays a specific role as a negative regulator of insulin signaling pathways and is a validated therapeutic target for Type 2 diabetes. Previously, arylbenzofurans were reported to have inhibitory activity against PTP1B. However, detailed investigation regardin...

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Bibliographic Details
Main Authors:	Srijan Shrestha, Su Hui Seong, Seul Gi Park, Byung Sun Min, Hyun Ah Jung, Jae Sue Choi
Format:	Article
Language:	English
Published:	MDPI AG 2019-08-01
Series:	Molecules
Subjects:	2-arylbenzofurans PTP1B T2DM in silico studies
Online Access:	https://www.mdpi.com/1420-3049/24/16/2893

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