Selective COX-2 Inhibitors: Road from Success to Controversy and the Quest for Repurposing

Selective COX-2 Inhibitors: Road from Success to Controversy and the Quest for Repurposing

The introduction of selective COX-2 inhibitors (so-called ‘coxibs’) has demonstrated tremendous commercial success due to their claimed lower potential of serious gastrointestinal adverse effects than traditional NSAIDs. However, following the repeated questioning on safety concerns, the coxibs ‘con...

Full description

Bibliographic Details
Main Authors: Afaf A. El-Malah, Magdy M. Gineinah, Pran Kishore Deb, Ahdab N. Khayyat, Monika Bansal, Katharigatta N. Venugopala, Anfal S. Aljahdali
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Pharmaceuticals
Subjects:
selective COX-2 inhibitors
coxibs
drug repurposing
celecoxib
valdecoxib
Vioxx
Online Access:https://www.mdpi.com/1424-8247/15/7/827

Similar Items

Similar Items