High Density of CD16+ Tumor-Infiltrating Immune Cells in Recurrent Ovarian Cancer Is Associated with Enhanced Responsiveness to Chemotherapy and Prolonged Overall Survival

High Density of CD16+ Tumor-Infiltrating Immune Cells in Recurrent Ovarian Cancer Is Associated with Enhanced Responsiveness to Chemotherapy and Prolonged Overall Survival

Background: Ovarian cancer (OC) is the most aggressive and fatal malignancy of the female reproductive system. Debulking surgery with adjuvant chemotherapy represents the standard treatment, but recurrence rates are particularly high. Over the past decades, the association between the immune system...

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Bibliographic Details
Main Authors: Alexandros Lalos, Ornella Neri, Caner Ercan, Alexander Wilhelm, Sebastian Staubli, Alberto Posabella, Benjamin Weixler, Luigi Terracciano, Salvatore Piscuoglio, Sylvia Stadlmann, Giulio C. Spagnoli, Raoul A. Droeser, Gad Singer
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Cancers
Subjects:
ovarian cancer
CD16
tissue microarray
immunohistochemistry
prognosis
biomarker
Online Access:https://www.mdpi.com/2072-6694/13/22/5783

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