Red blood cell-derived arginase release in hemolytic uremic syndrome

Red blood cell-derived arginase release in hemolytic uremic syndrome

Abstract Background Hemolysis is a cardinal feature of hemolytic uremic syndrome (HUS) and during hemolysis excess arginase 1 is released from red blood cells. Increased arginase activity leads to reduced L-arginine, as it is converted to urea and L-ornithine, and thereby reduced nitric oxide bioava...

Full description

Bibliographic Details
Main Authors: Niklas Friberg, Ida Arvidsson, Ashmita Tontanahal, Ann-Charlotte Kristoffersson, Magnus Gram, Bernard S. Kaplan, Diana Karpman
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Translational Medicine
Subjects:
Arginase
Hemolytic uremic syndrome
Thrombotic microangiopathy
Nitric oxide
Shiga toxin
Online Access:https://doi.org/10.1186/s12967-023-04824-x

Similar Items

Similar Items