Development of a method for preparing polymer microspheres containing immobilized diclofenac
The dependence of characteristics of microspheres and the kinetics of drug release from the particles on the type and intensity of mechanical action on the emulsion upon the preparation of polymeric microspheres containing encapsulated diclofenac based on a copolymer of lactic and glycolic acids was...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
MIREA - Russian Technological University
2015-08-01
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| Series: | Тонкие химические технологии |
| Subjects: | |
| Online Access: | https://www.finechem-mirea.ru/jour/article/view/244 |
| _version_ | 1797882051298328576 |
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| author | Tam Tkhi Nguen S. A. Kedik V. V. Suslov E. A. Shnyak E. V. Vorfolomeeva E. V. Nikonorova |
| author_facet | Tam Tkhi Nguen S. A. Kedik V. V. Suslov E. A. Shnyak E. V. Vorfolomeeva E. V. Nikonorova |
| author_sort | Tam Tkhi Nguen |
| collection | DOAJ |
| description | The dependence of characteristics of microspheres and the kinetics of drug release from the particles on the type and intensity of mechanical action on the emulsion upon the preparation of polymeric microspheres containing encapsulated diclofenac based on a copolymer of lactic and glycolic acids was investigated. According to the results of the research conditions were selected for the production of microspheres with the gradual release of drug from the particles during two weeks. The polymer microspheres are promising for further study and creation of prolonged dosage forms of diclofenac on their basis. |
| first_indexed | 2024-04-10T03:29:55Z |
| format | Article |
| id | doaj.art-8c7fc305722746c49030ee6ff1ca2deb |
| institution | Directory Open Access Journal |
| issn | 2410-6593 2686-7575 |
| language | Russian |
| last_indexed | 2024-04-10T03:29:55Z |
| publishDate | 2015-08-01 |
| publisher | MIREA - Russian Technological University |
| record_format | Article |
| series | Тонкие химические технологии |
| spelling | doaj.art-8c7fc305722746c49030ee6ff1ca2deb2023-03-13T07:25:36ZrusMIREA - Russian Technological UniversityТонкие химические технологии2410-65932686-75752015-08-011042731238Development of a method for preparing polymer microspheres containing immobilized diclofenacTam Tkhi Nguen0S. A. Kedik1V. V. Suslov2E. A. Shnyak3E. V. Vorfolomeeva4E. V. Nikonorova5M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571The dependence of characteristics of microspheres and the kinetics of drug release from the particles on the type and intensity of mechanical action on the emulsion upon the preparation of polymeric microspheres containing encapsulated diclofenac based on a copolymer of lactic and glycolic acids was investigated. According to the results of the research conditions were selected for the production of microspheres with the gradual release of drug from the particles during two weeks. The polymer microspheres are promising for further study and creation of prolonged dosage forms of diclofenac on their basis.https://www.finechem-mirea.ru/jour/article/view/244diclofenac, copolymer of lactic and glycolic acids, microspheres |
| spellingShingle | Tam Tkhi Nguen S. A. Kedik V. V. Suslov E. A. Shnyak E. V. Vorfolomeeva E. V. Nikonorova Development of a method for preparing polymer microspheres containing immobilized diclofenac Тонкие химические технологии diclofenac, copolymer of lactic and glycolic acids, microspheres |
| title | Development of a method for preparing polymer microspheres containing immobilized diclofenac |
| title_full | Development of a method for preparing polymer microspheres containing immobilized diclofenac |
| title_fullStr | Development of a method for preparing polymer microspheres containing immobilized diclofenac |
| title_full_unstemmed | Development of a method for preparing polymer microspheres containing immobilized diclofenac |
| title_short | Development of a method for preparing polymer microspheres containing immobilized diclofenac |
| title_sort | development of a method for preparing polymer microspheres containing immobilized diclofenac |
| topic | diclofenac, copolymer of lactic and glycolic acids, microspheres |
| url | https://www.finechem-mirea.ru/jour/article/view/244 |
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