Divergent immune landscapes of primary and syngeneic Kras-driven mouse tumor models

Abstract Immune cells play critical functions in cancer, and mice with intact immune systems are vital to understanding tumor immunology. Both genetically engineered mouse models (GEMMs) and syngeneic cell transplant approaches use immunocompetent mice to define immune-dependent events in tumor deve...

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Main Authors: Wade R. Gutierrez, Amanda Scherer, Gavin R. McGivney, Qierra R. Brockman, Vickie Knepper-Adrian, Emily A. Laverty, Grace A. Roughton, Rebecca D. Dodd
格式: Article
語言:English
出版: Nature Portfolio 2021-01-01
叢編:Scientific Reports
在線閱讀:https://doi.org/10.1038/s41598-020-80216-1