MicroRNA-146b regulates hepatic stellate cell activation via targeting of KLF4

MicroRNA-146b regulates hepatic stellate cell activation via targeting of KLF4

Background. We previously identified miR-146b as being up-regulated during the development of hepatic fibrosis using deep sequencing technology and gene expression analysis. However, the roles and related mechanisms of miR-146b in hepatic stellate cells (HSCs), which are involved in fibrogenesis and...

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Bibliographic Details
Main Authors: Shanfei Ge, Lunli Zhang, Jianping Xie, Fei Liu, Jinni He, Jinwen He, Xiaowei Wang, Tianxing Xiang
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Annals of Hepatology
Subjects:
miR-146b
KLF4
Hepatic stellate cell
Fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119311202

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