Ocular instillation of conditioned medium from mesenchymal stem cells is effective for dry eye syndrome by improving corneal barrier function
Abstract Dry eye syndrome (DES) is a chronic ocular disease that induces epithelial damage to the cornea by decreasing tear production and quality. Adequate treatment options have not been established for severe DES such as Sjogren’s syndrome due to complicated pathological conditions. To solve this...
Main Authors: | Tsutomu Imaizumi, Ryuhei Hayashi, Yuji Kudo, Xiaoqin Li, Kaito Yamaguchi, Shun Shibata, Toru Okubo, Tsuyoshi Ishii, Yoichi Honma, Kohji Nishida |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-08-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-40136-2 |
Similar Items
-
Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages
by: Shun Shibata, et al.
Published: (2018-11-01) -
Artificial Tear Instillation-Induced Changes in Corneal Topography
by: Yunjin Lee, et al.
Published: (2024-01-01) -
Effects of the dipeptide L-glutamic acid-L-tryptophan on dermatitis in mice and human keratinocytes
by: Shun Shibata, et al.
Published: (2022-01-01) -
Effect of colloidal silver nanoparticle solution instillation on the ultrastructure of the corneal epithelium and stroma
by: V.A. Ulyanov, et al.
Published: (2017-06-01) -
Generation of a TALEN-mediated, p63 knock-in in human induced pluripotent stem cells
by: Yuki Kobayashi, et al.
Published: (2017-12-01)