Editorial: Harnessing chemotherapy resistance and development of novel therapeutic strategies for acute leukemia with KMT2A (MLL)-gene rearrangements

Editorial: Harnessing chemotherapy resistance and development of novel therapeutic strategies for acute leukemia with KMT2A (MLL)-gene rearrangements

Bibliographic Details
Main Authors:	Maria Teresa Esposito, Anna Hagström-Andersson, Ronald W. Stam, Stefania Bortoluzzi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Pharmacology
Subjects:	KMT2A MLL ALL AML Leukemia drug repositioining
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.977741/full

Similar Items

Drug Repurposing for Targeting Acute Leukemia With KMT2A (MLL)—Gene Rearrangements
by: Alexia Tsakaneli, et al.
Published: (2021-09-01)

Novel Diagnostic and Therapeutic Options for KMT2A-Rearranged Acute Leukemias
by: Bruno A. Lopes, et al.
Published: (2022-06-01)

SETD2 in MLL-rearranged leukemia – a complex case
by: Anna Skucha, et al.
Published: (2018-07-01)

Preclinical Evaluation of Carfilzomib for Infant KMT2A-Rearranged Acute Lymphoblastic Leukemia
by: Laurence C. Cheung, et al.
Published: (2021-04-01)

Decitabine mildly attenuates MLL‐rearranged acute lymphoblastic leukemia in vivo, and represents a poor chemo‐sensitizer
by: Pauline Schneider, et al.
Published: (2020-11-01)

Rewiring the Epigenetic Networks in MLL-Rearranged Leukemias: Epigenetic Dysregulation and Pharmacological Interventions
by: Anthony K. N. Chan, et al.
Published: (2019-05-01)

Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia
by: Aditya Barve, et al.
Published: (2019-10-01)

RNA binding proteins in MLL-rearranged leukemia
by: Tiffany M. Tran, et al.
Published: (2022-10-01)

Acute lymphoblastic leukemia (ALL) with KMT2A gene rearrangement in infants - characteristic clinical picture based on a case report
by: Maria Kowalczuk, et al.
Published: (2022-03-01)

Expanding diagnostic criteria: Multiorgan T-Cell/myeloid mixed phenotype acute leukemia with t(v;11q23) KMT2A-rearrangement successfully treated by allogeneic stem cell transplant
by: Suhayb Syed, et al.
Published: (2022-01-01)

Impact of KMT2A Rearrangement and CSPG4 Expression in Pediatric Acute Myeloid Leukemia
by: Lina Marie Hoffmeister, et al.
Published: (2021-09-01)

DNA fragility at the KMT2A/MLL locus: insights from old and new technologies
by: Ian G. Cowell, et al.
Published: (2023-01-01)

Pediatric M5 acute myeloid leukemia with MLL-SEPT6 fusion and a favorable outcome
by: Alain Chebly, et al.
Published: (2021-01-01)

Acute myeloid leukemia cutis with KMT2A::MLLT3 fusion presenting with leonine facies
by: Bret Wankel, et al.
Published: (2024-01-01)

Essential Functions of MLL1 and MLL2 in Retinal Development and Cone Cell Maintenance
by: Chi Sun, et al.
Published: (2022-02-01)

Isolated leukemia cutis as extramedullary relapse of acute myeloid leukemia
by: Farinoosh Dadrass, et al.
Published: (2022-08-01)

Systematic In Vitro Evaluation of a Library of Approved and Pharmacologically Active Compounds for the Identification of Novel Candidate Drugs for KMT2A-Rearranged Leukemia
by: Mawar Karsa, et al.
Published: (2022-01-01)

Novel Compounds Synergize With Venetoclax to Target KMT2A-Rearranged Pediatric Acute Myeloid Leukemia
by: Claudia Tregnago, et al.
Published: (2022-01-01)

High-throughput drug screening reveals Pyrvinium pamoate as effective candidate against pediatric MLL-rearranged acute myeloid leukemia
by: Priscilla Wander, et al.
Published: (2021-05-01)

<i>MLL</i>-Rearranged Acute Leukemia with t(4;11)(q21;q23)—Current Treatment Options. Is There a Role for CAR-T Cell Therapy?
by: Oliver Britten, et al.
Published: (2019-10-01)

Lineage switch in relapse of acute leukemia with rearrangement of MLL gene (KMT2A). literature review and case reports
by: E. A. Zerkalenkova, et al.
Published: (2016-08-01)

TXNIP induces growth arrest and enhances ABT263‐induced apoptosis in mixed‐lineage leukemia‐rearranged acute myeloid leukemia cells
by: Mina Noura, et al.
Published: (2020-08-01)

Dysregulated transcriptional networks in KMT2A- and MLLT10-rearranged T-ALL
by: Huining Kang, et al.
Published: (2018-08-01)

A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1
by: Masashi Numata, et al.
Published: (2023-02-01)

Aggressive leukemia driven by MLL-AF9
by: Vaia Stavropoulou, et al.
Published: (2018-05-01)

Congenital B-lymphoblastic leukemia with a cryptic MLL rearrangement and post-treatment evolution to mixed phenotype acute leukemia
by: Elizabeth Moschiano, et al.
Published: (2016-01-01)

Pharmacological inhibition of LSD1 for the treatment of MLL-rearranged leukemia
by: Zizhen Feng, et al.
Published: (2016-03-01)

Prognostic value and outcome for acute lymphocytic leukemia in children with MLL rearrangement: a case-control study
by: Kun-yin Qiu, et al.
Published: (2022-12-01)

Irinotecan Induces Disease Remission in Xenograft Mouse Models of Pediatric <i>MLL</i>-Rearranged Acute Lymphoblastic Leukemia
by: Mark Kerstjens, et al.
Published: (2021-06-01)

Detection of 11q23 (MLL) rearrangements in infant acute lymphoblastic leukemia
by: G. A. Tsaur, et al.
Published: (2014-07-01)

Detection of 11q23 (MLL) rearrangements in infant acute lymphoblastic leukemia
by: G. A. Tsaur, et al.
Published: (2014-07-01)

Critical Roles of the Histone Methyltransferase MLL4/KMT2D in Murine Hepatic Steatosis Directed by ABL1 and PPARγ2
by: Dae-Hwan Kim, et al.
Published: (2016-11-01)

High-Throughput Drug Library Screening in Primary <i>KMT2A</i>-Rearranged Infant ALL Cells Favors the Identification of Drug Candidates That Activate P53 Signaling
by: Priscilla Wander, et al.
Published: (2022-03-01)

Development Refractoriness of MLL-Rearranged Human B Cell Acute Leukemias to Reprogramming into Pluripotency
by: Alvaro Muñoz-López, et al.
Published: (2016-10-01)

Updates in <i>KMT2A</i> Gene Rearrangement in Pediatric Acute Lymphoblastic Leukemia
by: Mateusz Górecki, et al.
Published: (2023-03-01)

Telomere Transcription in <i>MLL</i>-Rearranged Leukemia Cell Lines: Increased Levels of TERRA Associate with Lymphoid Lineage and Are Independent of Telomere Length and Ploidy
by: Corrado Caslini, et al.
Published: (2023-03-01)

MLL leukemia-associated rearrangements in peripheral blood lymphocytes from healthy individuals
by: María Sol Brassesco, et al.
Published: (2009-01-01)

Preferential induction of MLL (Mixed Lineage Leukemia) rearrangements in human lymphocyte cultures treated with etoposide
by: María Sol Brassesco, et al.
Published: (2009-01-01)

Murine Models of Acute Myeloid Leukemia
by: Kristen J. Kurtz, et al.
Published: (2022-06-01)

Corrigendum: Murine models of acute myeloid leukemia
by: Kristen J. Kurtz, et al.
Published: (2023-02-01)