Kaposi Sarcoma Mimicking Acute Flare of Ulcerative Colitis
Besides an AIDS-defining illness, Kaposi sarcoma (KS) is also seen in individuals on long-term immunosuppressant therapy. We report KS in a 70-year-old immunocompetent man, which initially mimicked acute flare of ulcerative colitis (UC). He was hospitalized multiple times for complaints of watery di...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2017-06-01
|
| Series: | Journal of Investigative Medicine High Impact Case Reports |
| Online Access: | https://doi.org/10.1177/2324709617713510 |
| _version_ | 1818131657391079424 |
|---|---|
| author | Vivek Kumar MD Parita Soni MD Mohit Garg MD Madina Abduraimova MD Jonathan Harris MD |
| author_facet | Vivek Kumar MD Parita Soni MD Mohit Garg MD Madina Abduraimova MD Jonathan Harris MD |
| author_sort | Vivek Kumar MD |
| collection | DOAJ |
| description | Besides an AIDS-defining illness, Kaposi sarcoma (KS) is also seen in individuals on long-term immunosuppressant therapy. We report KS in a 70-year-old immunocompetent man, which initially mimicked acute flare of ulcerative colitis (UC). He was hospitalized multiple times for complaints of watery diarrhea and tenesmus. Despite treatment with mesalamine, short courses of methylprednisolone, and one dose of infliximab, his symptoms improved only partially. He underwent colonoscopy, which revealed mild active colitis and a mass in the ascending colon. After treatment of acute flare with methylprednisone and mesalamine, he underwent total colectomy with end ileostomy. The histopathology confirmed stage I adenocarcinoma of colon. He continued to experience watery diarrhea, which was attributed to intractable UC, and he underwent protectomy several weeks later. The histopathology of rectum revealed KS. After surgery, watery diarrhea resolved completely. Review of literature suggests KS has been rarely reported in immunocompetent individuals with inflammatory bowel disease. |
| first_indexed | 2024-12-11T08:24:25Z |
| format | Article |
| id | doaj.art-8c8db70399f14c5fa879ba04945adfd4 |
| institution | Directory Open Access Journal |
| issn | 2324-7096 |
| language | English |
| last_indexed | 2024-12-11T08:24:25Z |
| publishDate | 2017-06-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Investigative Medicine High Impact Case Reports |
| spelling | doaj.art-8c8db70399f14c5fa879ba04945adfd42022-12-22T01:14:36ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962017-06-01510.1177/2324709617713510Kaposi Sarcoma Mimicking Acute Flare of Ulcerative ColitisVivek Kumar MD0Parita Soni MD1Mohit Garg MD2Madina Abduraimova MD3Jonathan Harris MD4Maimonides Medical Center, Brooklyn, NY, USAMaimonides Medical Center, Brooklyn, NY, USAMaimonides Medical Center, Brooklyn, NY, USAMaimonides Medical Center, Brooklyn, NY, USAMaimonides Medical Center, Brooklyn, NY, USABesides an AIDS-defining illness, Kaposi sarcoma (KS) is also seen in individuals on long-term immunosuppressant therapy. We report KS in a 70-year-old immunocompetent man, which initially mimicked acute flare of ulcerative colitis (UC). He was hospitalized multiple times for complaints of watery diarrhea and tenesmus. Despite treatment with mesalamine, short courses of methylprednisolone, and one dose of infliximab, his symptoms improved only partially. He underwent colonoscopy, which revealed mild active colitis and a mass in the ascending colon. After treatment of acute flare with methylprednisone and mesalamine, he underwent total colectomy with end ileostomy. The histopathology confirmed stage I adenocarcinoma of colon. He continued to experience watery diarrhea, which was attributed to intractable UC, and he underwent protectomy several weeks later. The histopathology of rectum revealed KS. After surgery, watery diarrhea resolved completely. Review of literature suggests KS has been rarely reported in immunocompetent individuals with inflammatory bowel disease.https://doi.org/10.1177/2324709617713510 |
| spellingShingle | Vivek Kumar MD Parita Soni MD Mohit Garg MD Madina Abduraimova MD Jonathan Harris MD Kaposi Sarcoma Mimicking Acute Flare of Ulcerative Colitis Journal of Investigative Medicine High Impact Case Reports |
| title | Kaposi Sarcoma Mimicking Acute Flare of Ulcerative Colitis |
| title_full | Kaposi Sarcoma Mimicking Acute Flare of Ulcerative Colitis |
| title_fullStr | Kaposi Sarcoma Mimicking Acute Flare of Ulcerative Colitis |
| title_full_unstemmed | Kaposi Sarcoma Mimicking Acute Flare of Ulcerative Colitis |
| title_short | Kaposi Sarcoma Mimicking Acute Flare of Ulcerative Colitis |
| title_sort | kaposi sarcoma mimicking acute flare of ulcerative colitis |
| url | https://doi.org/10.1177/2324709617713510 |
| work_keys_str_mv | AT vivekkumarmd kaposisarcomamimickingacuteflareofulcerativecolitis AT paritasonimd kaposisarcomamimickingacuteflareofulcerativecolitis AT mohitgargmd kaposisarcomamimickingacuteflareofulcerativecolitis AT madinaabduraimovamd kaposisarcomamimickingacuteflareofulcerativecolitis AT jonathanharrismd kaposisarcomamimickingacuteflareofulcerativecolitis |