Isolation and identification of three new chromones from the leaves of Pimenta dioica with cytotoxic, oestrogenic and anti-oestrogenic effects

Isolation and identification of three new chromones from the leaves of Pimenta dioica with cytotoxic, oestrogenic and anti-oestrogenic effects

Context: Pimenta dioica (L.) Merr. (Myrtaceae) is used in Costa Rican traditional medicine for women’s health. Our previous work showed that P. dioica extracts were oestrogenic. Objectives: This work identifies phytochemicals from P. dioica that are responsible for the plant’s oestrogen-like activit...

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Bibliographic Details
Main Authors: Brian J. Doyle, Temitope O. Lawal, Tracie D. Locklear, Lorraina Hernandez, Alice L. Perez, Udeshi Patel, Shitalben Patel, Gail B. Mahady
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Pharmaceutical Biology
Subjects:
allspice
apoptosis
breast cancer
caspase
costa rica
ethnomedicine
oestrogen
latin america
menopause
Online Access:http://dx.doi.org/10.1080/13880209.2018.1448873

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