Dysfunction of Foxp3<sup>+</sup> Regulatory T Cells Induces Dysbiosis of Gut Microbiota via Aberrant Binding of Immunoglobulins to Microbes in the Intestinal Lumen

Dysfunction of Foxp3<sup>+</sup> Regulatory T Cells Induces Dysbiosis of Gut Microbiota via Aberrant Binding of Immunoglobulins to Microbes in the Intestinal Lumen

Foxp3<sup>+</sup> regulatory T (Treg) cells prevent excessive immune responses against dietary antigens and commensal bacteria in the intestine. Moreover, Treg cells contribute to the establishment of a symbiotic relationship between the host and gut microbes, partly through immunoglobul...

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Bibliographic Details
Main Authors: Kouhei Koshida, Mitsuki Ito, Kyosuke Yakabe, Yoshimitsu Takahashi, Yuki Tai, Ryouhei Akasako, Tatsuki Kimizuka, Shunsuke Takano, Natsumi Sakamoto, Kei Haniuda, Shuhei Ogawa, Shunsuke Kimura, Yun-Gi Kim, Koji Hase, Yohsuke Harada
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:International Journal of Molecular Sciences
Subjects:
Foxp3<sup>+</sup> regulatory T cell
gut microbiota
immunoglobulin G
immunoglobulin A
helper T cell
Online Access:https://www.mdpi.com/1422-0067/24/10/8549

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https://www.mdpi.com/1422-0067/24/10/8549

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