Proteomic analysis of a NAP1 Clostridium difficile clinical isolate resistant to metronidazole.

Proteomic analysis of a NAP1 Clostridium difficile clinical isolate resistant to metronidazole.

BACKGROUND: Clostridium difficile is an anaerobic, Gram-positive bacterium that has been implicated as the leading cause of antibiotic-associated diarrhea. Metronidazole is currently the first-line treatment for mild to moderate C. difficile infections. Our laboratory isolated a strain of C. diffici...

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Bibliographic Details
Main Authors: Patrick M Chong, Tarah Lynch, Stuart McCorrister, Pamela Kibsey, Mark Miller, Denise Gravel, Garrett R Westmacott, Michael R Mulvey, Canadian Nosocomial Infection Surveillance Program (CNISP)
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3882210?pdf=render

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