Elevated neurofilament light chain CSF/serum ratio indicates impaired CSF outflow in idiopathic intracranial hypertension

Elevated neurofilament light chain CSF/serum ratio indicates impaired CSF outflow in idiopathic intracranial hypertension

Abstract Background Impaired cerebrospinal fluid (CSF) homeostasis is central to the pathogenesis of idiopathic intracranial hypertension (IIH), although the precise mechanisms involved are still not completely understood. The aim of the current study was to assess the CSF/serum ratio of neurofilame...

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Bibliographic Details
Main Authors: Sinah Engel, Johannes Halcour, Erik Ellwardt, Timo Uphaus, Falk Steffen, Frauke Zipp, Stefan Bittner, Felix Luessi
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Fluids and Barriers of the CNS
Online Access:https://doi.org/10.1186/s12987-022-00403-2

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