Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review

Persons diagnosed with dementia are often faced with challenges related to polypharmacy and inappropriate medication use and could benefit from regular medication reviews. However, the benefit of such reviews has not been examined in this population. Therefore, the current scoping review was designe...

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Main Authors: Rishabh Sharma, Neil Mahajan, Sarah Abu Fadaleh, Hawa Patel, Jessica Ivo, Sadaf Faisal, Feng Chang, Linda Lee, Tejal Patel
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmacy
Subjects:
Online Access:https://www.mdpi.com/2226-4787/11/5/168
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author Rishabh Sharma
Neil Mahajan
Sarah Abu Fadaleh
Hawa Patel
Jessica Ivo
Sadaf Faisal
Feng Chang
Linda Lee
Tejal Patel
author_facet Rishabh Sharma
Neil Mahajan
Sarah Abu Fadaleh
Hawa Patel
Jessica Ivo
Sadaf Faisal
Feng Chang
Linda Lee
Tejal Patel
author_sort Rishabh Sharma
collection DOAJ
description Persons diagnosed with dementia are often faced with challenges related to polypharmacy and inappropriate medication use and could benefit from regular medication reviews. However, the benefit of such reviews has not been examined in this population. Therefore, the current scoping review was designed to identify the gaps in the current knowledge regarding the impact of medication reviews on the clinical outcomes in older adults with dementia. Relevant studies were identified by searching three databases (Ovid MEDLINE, Ovid EMBASE, and Scopus) from inception to January 2022 with a combination of keywords and medical subject headings. After the removal of duplicates and ineligible articles, 22 publications of the initial 8346 were included in this review. A total of 57 outcomes were identified, including those pertaining to the evaluation of medication use (n = 17), drug-related interventions (n = 11), drug-related problems (n = 10), dementia-related behavioral symptoms (n = 8), cost-effectiveness (n = 2), drug-related hospital admissions (n = 1), as well as outcomes classified as other (n = 7). Gaps identified through this scoping review included the paucity of studies measuring the impact of medication reviews on the medication management capacity and medication adherence, quality of life, and mortality.
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spelling doaj.art-8c9558baf6e64be5b84ddd4b554eebaa2023-11-19T17:46:12ZengMDPI AGPharmacy2226-47872023-10-0111516810.3390/pharmacy11050168Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping ReviewRishabh Sharma0Neil Mahajan1Sarah Abu Fadaleh2Hawa Patel3Jessica Ivo4Sadaf Faisal5Feng Chang6Linda Lee7Tejal Patel8School of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, ON N2G 1C5, CanadaFaculty of Health, Western University, 1151 Richmond St, London, ON N6A 5B9, CanadaSchool of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, ON N2G 1C5, CanadaSchool of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, ON N2G 1C5, CanadaSchool of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, ON N2G 1C5, CanadaSchool of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, ON N2G 1C5, CanadaSchool of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, ON N2G 1C5, CanadaCFFM MINT Memory Clinic, 25 Joseph St, Kitchener, ON N2G 4X6, CanadaSchool of Pharmacy, University of Waterloo, 10 Victoria St S A, Kitchener, ON N2G 1C5, CanadaPersons diagnosed with dementia are often faced with challenges related to polypharmacy and inappropriate medication use and could benefit from regular medication reviews. However, the benefit of such reviews has not been examined in this population. Therefore, the current scoping review was designed to identify the gaps in the current knowledge regarding the impact of medication reviews on the clinical outcomes in older adults with dementia. Relevant studies were identified by searching three databases (Ovid MEDLINE, Ovid EMBASE, and Scopus) from inception to January 2022 with a combination of keywords and medical subject headings. After the removal of duplicates and ineligible articles, 22 publications of the initial 8346 were included in this review. A total of 57 outcomes were identified, including those pertaining to the evaluation of medication use (n = 17), drug-related interventions (n = 11), drug-related problems (n = 10), dementia-related behavioral symptoms (n = 8), cost-effectiveness (n = 2), drug-related hospital admissions (n = 1), as well as outcomes classified as other (n = 7). Gaps identified through this scoping review included the paucity of studies measuring the impact of medication reviews on the medication management capacity and medication adherence, quality of life, and mortality.https://www.mdpi.com/2226-4787/11/5/168older adultsdementiamedication reviewdrug-related problems
spellingShingle Rishabh Sharma
Neil Mahajan
Sarah Abu Fadaleh
Hawa Patel
Jessica Ivo
Sadaf Faisal
Feng Chang
Linda Lee
Tejal Patel
Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review
Pharmacy
older adults
dementia
medication review
drug-related problems
title Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review
title_full Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review
title_fullStr Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review
title_full_unstemmed Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review
title_short Medication Reviews and Clinical Outcomes in Persons with Dementia: A Scoping Review
title_sort medication reviews and clinical outcomes in persons with dementia a scoping review
topic older adults
dementia
medication review
drug-related problems
url https://www.mdpi.com/2226-4787/11/5/168
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