Development of a CRISPR/Cas9 system against ruminant animal brucellosis

Development of a CRISPR/Cas9 system against ruminant animal brucellosis

Abstract Background Brucellosis, caused by several Brucella species, such as the bacterium Brucella melitensis, is considered one of the most severe zoonotic diseases worldwide. Not only does it affect ruminant animal populations, leading to a substantial financial burden for stockbreeders, but also...

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Bibliographic Details
Main Authors: Garyfalia Karponi, Spyridon K. Kritas, Gina Papadopoulou, Elissavet-Kalliopi Akrioti, Eleni Papanikolaou, Evanthia Petridou
Format: Article
Language:English
Published: BMC 2019-11-01
Series:BMC Veterinary Research
Subjects:
Brucellosis
Gene therapy
Viral vectors
Ruminant animals
Macrophages
Online Access:http://link.springer.com/article/10.1186/s12917-019-2179-z

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