Characterizing advanced breast cancer heterogeneity and treatment resistance through serial biopsies and comprehensive analytics

Characterizing advanced breast cancer heterogeneity and treatment resistance through serial biopsies and comprehensive analytics

Abstract Molecular heterogeneity in metastatic breast cancer presents multiple clinical challenges in accurately characterizing and treating the disease. Current diagnostic approaches offer limited ability to assess heterogeneity that exists among multiple metastatic lesions throughout the treatment...

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Bibliographic Details
Main Authors: Allen Li, Jamie M. Keck, Swapnil Parmar, Janice Patterson, Marilyne Labrie, Allison L. Creason, Brett E. Johnson, Molly Downey, George Thomas, Carol Beadling, Laura M. Heiser, Annette Kolodzie, Alexander R. Guimaraes, Christopher L. Corless, Joe W. Gray, Gordon B. Mills, Raymond C. Bergan, Zahi I. Mitri
Format: Article
Language:English
Published: Nature Portfolio 2021-03-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-021-00165-4

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