A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor
Gastric mixed adenocarcinoma-neuroendocrine tumor (NET) is a rare composite tumor, and a limited number of studies have reported on it. A 77-year-old man was admitted to our hospital because of acute cholecystitis. He underwent a cholecystectomy. Esophagogastroduodenoscopy during his admission revea...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2021-03-01
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| Series: | Case Reports in Gastroenterology |
| Subjects: | |
| Online Access: | http://prod.karger.com/Article/FullText/513802 |
| _version_ | 1818947019432001536 |
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| author | Yoshifumi Sano Shoichi Saito Hiroshi Kawachi Jun Tsutsumi Junko Fujisaki |
| author_facet | Yoshifumi Sano Shoichi Saito Hiroshi Kawachi Jun Tsutsumi Junko Fujisaki |
| author_sort | Yoshifumi Sano |
| collection | DOAJ |
| description | Gastric mixed adenocarcinoma-neuroendocrine tumor (NET) is a rare composite tumor, and a limited number of studies have reported on it. A 77-year-old man was admitted to our hospital because of acute cholecystitis. He underwent a cholecystectomy. Esophagogastroduodenoscopy during his admission revealed a slightly elevated tumor, and biopsy demonstrated a well-differentiated tubular adenocarcinoma. The tumor was resected completely by endoscopic submucosal dissection. Histological findings showed that it measured 9 mm in diameter, was located within the mucosa, and consisted of well-differentiated tubular adenocarcinoma and a NET G1. The NET was covered with adenocarcinoma and both components exhibited histological continuity. The NET and a part of the adenocarcinoma component showed a positive reaction for chromogranin A and synaptophysin. Neither enterochromaffin-like cell hyperplasia nor endocrine cell micronest surrounded the tumor. The diagnosis was gastric mixed adenocarcinoma-NET. The histological continuity between the two components can be likened to the same histogenesis. |
| first_indexed | 2024-12-20T08:24:15Z |
| format | Article |
| id | doaj.art-8ca09384487e4cf48f13e395b8ce0d05 |
| institution | Directory Open Access Journal |
| issn | 1662-0631 |
| language | English |
| last_indexed | 2024-12-20T08:24:15Z |
| publishDate | 2021-03-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj.art-8ca09384487e4cf48f13e395b8ce0d052022-12-21T19:46:54ZengKarger PublishersCase Reports in Gastroenterology1662-06312021-03-0115132333110.1159/000513802513802A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine TumorYoshifumi Sano0Shoichi Saito1Hiroshi Kawachi2Jun Tsutsumi3Junko Fujisaki4Department of Endoscopy, Mashiko Hospital, Kawaguchi, JapanDepartment of Gastroenterology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, JapanDepartment of Pathology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, JapanDepartment of Surgery, Mashiko Hospital, Kawaguchi, JapanDepartment of Gastroenterology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, JapanGastric mixed adenocarcinoma-neuroendocrine tumor (NET) is a rare composite tumor, and a limited number of studies have reported on it. A 77-year-old man was admitted to our hospital because of acute cholecystitis. He underwent a cholecystectomy. Esophagogastroduodenoscopy during his admission revealed a slightly elevated tumor, and biopsy demonstrated a well-differentiated tubular adenocarcinoma. The tumor was resected completely by endoscopic submucosal dissection. Histological findings showed that it measured 9 mm in diameter, was located within the mucosa, and consisted of well-differentiated tubular adenocarcinoma and a NET G1. The NET was covered with adenocarcinoma and both components exhibited histological continuity. The NET and a part of the adenocarcinoma component showed a positive reaction for chromogranin A and synaptophysin. Neither enterochromaffin-like cell hyperplasia nor endocrine cell micronest surrounded the tumor. The diagnosis was gastric mixed adenocarcinoma-NET. The histological continuity between the two components can be likened to the same histogenesis.http://prod.karger.com/Article/FullText/513802stomachcomposite tumormixed adenocarcinoma-neuroendocrine tumorendoscopic submucosal dissection |
| spellingShingle | Yoshifumi Sano Shoichi Saito Hiroshi Kawachi Jun Tsutsumi Junko Fujisaki A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor Case Reports in Gastroenterology stomach composite tumor mixed adenocarcinoma-neuroendocrine tumor endoscopic submucosal dissection |
| title | A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
| title_full | A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
| title_fullStr | A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
| title_full_unstemmed | A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
| title_short | A Gastric Intramucosal Mixed Adenocarcinoma-Neuroendocrine Tumor |
| title_sort | gastric intramucosal mixed adenocarcinoma neuroendocrine tumor |
| topic | stomach composite tumor mixed adenocarcinoma-neuroendocrine tumor endoscopic submucosal dissection |
| url | http://prod.karger.com/Article/FullText/513802 |
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