Perioperative Management of Chronic Antithrombotic Agents in Elective Hip and Knee Arthroplasty

Total hip and knee arthroplasty are common major orthopedic operations being performed on an increasing number of patients. Many patients undergoing total joint arthroplasty (TJA) are on chronic antithrombotic agents due to other medical conditions, such as atrial fibrillation or acute coronary synd...

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Main Authors: Daniel C. Santana, Matthew J. Hadad, Ahmed Emara, Alison K. Klika, Wael Barsoum, Robert M. Molloy, Viktor E. Krebs, Michael R. Bloomfield, Nicolas S. Piuzzi
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1010-660X/57/2/188
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author Daniel C. Santana
Matthew J. Hadad
Ahmed Emara
Alison K. Klika
Wael Barsoum
Robert M. Molloy
Viktor E. Krebs
Michael R. Bloomfield
Nicolas S. Piuzzi
author_facet Daniel C. Santana
Matthew J. Hadad
Ahmed Emara
Alison K. Klika
Wael Barsoum
Robert M. Molloy
Viktor E. Krebs
Michael R. Bloomfield
Nicolas S. Piuzzi
author_sort Daniel C. Santana
collection DOAJ
description Total hip and knee arthroplasty are common major orthopedic operations being performed on an increasing number of patients. Many patients undergoing total joint arthroplasty (TJA) are on chronic antithrombotic agents due to other medical conditions, such as atrial fibrillation or acute coronary syndrome. Given the risk of bleeding associated with TJAs, as well as the risk of thromboembolic events in the post-operative period, the management of chronic antithrombotic agents perioperatively is critical to achieving successful outcomes in arthroplasty. In this review, we provide a concise overview of society guidelines regarding the perioperative management of chronic antithrombotic agents in the setting of elective TJAs and summarize the recent literature that may inform future guidelines. Ultimately, antithrombotic regimen management should be patient-specific, in consultation with cardiology, internal medicine, hematology, and other physicians who play an essential role in perioperative care.
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spelling doaj.art-8ca1adbf61ec40b082757e2ffc1bc4722023-09-03T00:16:10ZengMDPI AGMedicina1010-660X2021-02-015718818810.3390/medicina57020188Perioperative Management of Chronic Antithrombotic Agents in Elective Hip and Knee ArthroplastyDaniel C. Santana0Matthew J. Hadad1Ahmed Emara2Alison K. Klika3Wael Barsoum4Robert M. Molloy5Viktor E. Krebs6Michael R. Bloomfield7Nicolas S. Piuzzi8Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USAHealthcare Outcomes Performance Company (HOPCo), Phoenix, AZ 85023, USADepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USADepartment of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH 44195, USATotal hip and knee arthroplasty are common major orthopedic operations being performed on an increasing number of patients. Many patients undergoing total joint arthroplasty (TJA) are on chronic antithrombotic agents due to other medical conditions, such as atrial fibrillation or acute coronary syndrome. Given the risk of bleeding associated with TJAs, as well as the risk of thromboembolic events in the post-operative period, the management of chronic antithrombotic agents perioperatively is critical to achieving successful outcomes in arthroplasty. In this review, we provide a concise overview of society guidelines regarding the perioperative management of chronic antithrombotic agents in the setting of elective TJAs and summarize the recent literature that may inform future guidelines. Ultimately, antithrombotic regimen management should be patient-specific, in consultation with cardiology, internal medicine, hematology, and other physicians who play an essential role in perioperative care.https://www.mdpi.com/1010-660X/57/2/188arthroplastyanticoagulationvenous thromboembolismmajor bleedingsurgical complications
spellingShingle Daniel C. Santana
Matthew J. Hadad
Ahmed Emara
Alison K. Klika
Wael Barsoum
Robert M. Molloy
Viktor E. Krebs
Michael R. Bloomfield
Nicolas S. Piuzzi
Perioperative Management of Chronic Antithrombotic Agents in Elective Hip and Knee Arthroplasty
Medicina
arthroplasty
anticoagulation
venous thromboembolism
major bleeding
surgical complications
title Perioperative Management of Chronic Antithrombotic Agents in Elective Hip and Knee Arthroplasty
title_full Perioperative Management of Chronic Antithrombotic Agents in Elective Hip and Knee Arthroplasty
title_fullStr Perioperative Management of Chronic Antithrombotic Agents in Elective Hip and Knee Arthroplasty
title_full_unstemmed Perioperative Management of Chronic Antithrombotic Agents in Elective Hip and Knee Arthroplasty
title_short Perioperative Management of Chronic Antithrombotic Agents in Elective Hip and Knee Arthroplasty
title_sort perioperative management of chronic antithrombotic agents in elective hip and knee arthroplasty
topic arthroplasty
anticoagulation
venous thromboembolism
major bleeding
surgical complications
url https://www.mdpi.com/1010-660X/57/2/188
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