Recent Advances in Doxorubicin Formulation to Enhance Pharmacokinetics and Tumor Targeting

Recent Advances in Doxorubicin Formulation to Enhance Pharmacokinetics and Tumor Targeting

Doxorubicin (DOX), a widely used drug in cancer chemotherapy, induces cell death via multiple intracellular interactions, generating reactive oxygen species and DNA-adducted configurations that induce apoptosis, topoisomerase II inhibition, and histone eviction. Despite its wide therapeutic efficacy...

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Bibliographic Details
Main Authors:	Jihoon Lee, Min-Koo Choi, Im-Sook Song
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Series:	Pharmaceuticals
Subjects:	doxorubicin (DOX) formulation strategy drug resistance oral formulation
Online Access:	https://www.mdpi.com/1424-8247/16/6/802

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