Structural and functional characterization of recombinant human growth hormone isolated from transgenic pig milk.
This study aimed to establish and reproduce transgenic pigs expressing human growth hormone (hGH) in their milk. We also aimed to purify hGH from the milk, to characterize the purified protein, and to assess the potential of our model for mass production of therapeutic proteins using transgenic tech...
Main Authors: | So-Young Lee, Joo-Hee Han, Eun-Kyeong Lee, Young Kyu Kim, Seo-Ah Hwang, Sung-Hyun Lee, Maria Kim, Gye Yoon Cho, Jae-Ha Hwang, Su-Jin Kim, Jae-Gyu Yoo, Seong-Keun Cho, Kyung-Ju Lee, Weon-Ki Cho |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0236788 |
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