Effectiveness of Percutaneous Ethanol Injection Therapy Compared to Parathyroidectomy in the Management of Secondary and Tertiary Hyperparathyroidism
Background: Secondary hyperparathyroidism (SHPT) and tertiary hyperparathyroidism (THPT) are a common complication of chronic renal failure. Percutaneous ethanol injection therapy (PEIT) has been used as alternative to surgery, but its effectiveness is inconsistent. Objectives: The objective of the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical and Scientific Publishers Pvt. Ltd.
2019-01-01
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| Series: | The Arab Journal of Interventional Radiology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/AJIR.AJIR_37_18 |
| Summary: | Background: Secondary hyperparathyroidism (SHPT) and tertiary hyperparathyroidism (THPT) are a common complication of chronic renal failure. Percutaneous ethanol injection therapy (PEIT) has been used as alternative to surgery, but its effectiveness is inconsistent. Objectives: The objective of the study is to evaluate the effectiveness of PEIT in the management of patients with SHPT and THPT. Materials and Methods: Ninety-one patients with chronic renal failure and SHPT or THPT were treated with PEIT (n = 55) and surgery (n = 36) between January 2006 and July 2015. The medical records, imaging studies, and ablation techniques were reviewed to assess the efficacy of each treatment modality and complications. Results: Parathyroid hormone (PTH) level after treatment <160 pg/mL was used to indicate success of treatment. PEIT showed lower effectiveness compared to surgery (1.8% vs. 61.1%). There was no complication in PEIT group. Symptomatic hypocalcemia was found 11.1% in surgery group. Conclusion: PEIT in treatment of secondary and THPT was much less effective than surgery due to large nodule sizes, high levels of PTH, and multiple parathyroid nodules. |
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| ISSN: | 2542-7075 2542-7083 |