Carvacrol and Thymol Content Affects the Antioxidant and Antibacterial Activity of <i>Origanum compactum</i> and <i>Thymus zygis</i> Essential Oils
Essential oils are of great interest due to their potent pharmaceutical and biological activities. In this study, essential oils extracted from <i>Origanum compactum</i> and <i>Thymus zygis</i> originating from the Middle Atlas of Morocco were investigated. Their chemical com...
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MDPI AG
2024-01-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/13/2/139 |
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| author | Mounia Chroho Youssef Rouphael Spyridon A. Petropoulos Latifa Bouissane |
| author_facet | Mounia Chroho Youssef Rouphael Spyridon A. Petropoulos Latifa Bouissane |
| author_sort | Mounia Chroho |
| collection | DOAJ |
| description | Essential oils are of great interest due to their potent pharmaceutical and biological activities. In this study, essential oils extracted from <i>Origanum compactum</i> and <i>Thymus zygis</i> originating from the Middle Atlas of Morocco were investigated. Their chemical compositions were analyzed using gas chromatography and mass spectrometry, while the assessment of the trapping power of the radical (DPPH: 1,1-diphenyl-2-picrylhydrazyl) and the reducing antioxidant potential of ferric ions (FRAP: Ferric Reducing Antioxidant Power) were performed in order to evaluate the antioxidant activity. Their antibacterial potency was tested against six bacterial strains through the disk diffusion method. The chromatography analyses of the extracted essential oils highlighted the presence of two main components, namely carvacrol at 75.70% in <i>O. compactum</i> and thymol at 40.67% in <i>T. zygis</i>. The antioxidant activity tests showed that both essential oils demonstrated a significant antioxidant activity comparable to the positive control (e.g., ascorbic acid). The antibacterial activity results showed a strong antimicrobial effect for both essential oils, compared to synthetic antibiotics. This study affirms the presence of bioactive components with interesting antioxidant and antibacterial activities in the essential oils extracted from <i>Origanum compactum</i> and <i>Thymus zygis</i>, which could find several applications in the food and pharmaceutical industries through the substitution of synthetic antioxidants and antibiotics. |
| first_indexed | 2024-03-07T22:44:43Z |
| format | Article |
| id | doaj.art-8ca94a31bd6648c3be72b7061bddbd81 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-07T22:44:43Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-8ca94a31bd6648c3be72b7061bddbd812024-02-23T15:05:02ZengMDPI AGAntibiotics2079-63822024-01-0113213910.3390/antibiotics13020139Carvacrol and Thymol Content Affects the Antioxidant and Antibacterial Activity of <i>Origanum compactum</i> and <i>Thymus zygis</i> Essential OilsMounia Chroho0Youssef Rouphael1Spyridon A. Petropoulos2Latifa Bouissane3Molecular Chemistry, Materials and Catalysis Laboratory, Faculty of Sciences and Technologies, Sultan Moulay Slimane University, BP 523, Beni-Mellal 23000, MoroccoDepartment of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici, ItalyDepartment of Agriculture, Crop Production and Rural Environment, University of Thessaly, Fytokou Street, 38446 Volos, GreeceMolecular Chemistry, Materials and Catalysis Laboratory, Faculty of Sciences and Technologies, Sultan Moulay Slimane University, BP 523, Beni-Mellal 23000, MoroccoEssential oils are of great interest due to their potent pharmaceutical and biological activities. In this study, essential oils extracted from <i>Origanum compactum</i> and <i>Thymus zygis</i> originating from the Middle Atlas of Morocco were investigated. Their chemical compositions were analyzed using gas chromatography and mass spectrometry, while the assessment of the trapping power of the radical (DPPH: 1,1-diphenyl-2-picrylhydrazyl) and the reducing antioxidant potential of ferric ions (FRAP: Ferric Reducing Antioxidant Power) were performed in order to evaluate the antioxidant activity. Their antibacterial potency was tested against six bacterial strains through the disk diffusion method. The chromatography analyses of the extracted essential oils highlighted the presence of two main components, namely carvacrol at 75.70% in <i>O. compactum</i> and thymol at 40.67% in <i>T. zygis</i>. The antioxidant activity tests showed that both essential oils demonstrated a significant antioxidant activity comparable to the positive control (e.g., ascorbic acid). The antibacterial activity results showed a strong antimicrobial effect for both essential oils, compared to synthetic antibiotics. This study affirms the presence of bioactive components with interesting antioxidant and antibacterial activities in the essential oils extracted from <i>Origanum compactum</i> and <i>Thymus zygis</i>, which could find several applications in the food and pharmaceutical industries through the substitution of synthetic antioxidants and antibiotics.https://www.mdpi.com/2079-6382/13/2/139chemical compositionhydrodistillationLamiaceaeantioxidant capacityDPPHFRAP |
| spellingShingle | Mounia Chroho Youssef Rouphael Spyridon A. Petropoulos Latifa Bouissane Carvacrol and Thymol Content Affects the Antioxidant and Antibacterial Activity of <i>Origanum compactum</i> and <i>Thymus zygis</i> Essential Oils Antibiotics chemical composition hydrodistillation Lamiaceae antioxidant capacity DPPH FRAP |
| title | Carvacrol and Thymol Content Affects the Antioxidant and Antibacterial Activity of <i>Origanum compactum</i> and <i>Thymus zygis</i> Essential Oils |
| title_full | Carvacrol and Thymol Content Affects the Antioxidant and Antibacterial Activity of <i>Origanum compactum</i> and <i>Thymus zygis</i> Essential Oils |
| title_fullStr | Carvacrol and Thymol Content Affects the Antioxidant and Antibacterial Activity of <i>Origanum compactum</i> and <i>Thymus zygis</i> Essential Oils |
| title_full_unstemmed | Carvacrol and Thymol Content Affects the Antioxidant and Antibacterial Activity of <i>Origanum compactum</i> and <i>Thymus zygis</i> Essential Oils |
| title_short | Carvacrol and Thymol Content Affects the Antioxidant and Antibacterial Activity of <i>Origanum compactum</i> and <i>Thymus zygis</i> Essential Oils |
| title_sort | carvacrol and thymol content affects the antioxidant and antibacterial activity of i origanum compactum i and i thymus zygis i essential oils |
| topic | chemical composition hydrodistillation Lamiaceae antioxidant capacity DPPH FRAP |
| url | https://www.mdpi.com/2079-6382/13/2/139 |
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