Inference of Subpathway Activity Profiles Reveals Metabolism Abnormal Subpathway Regions in Glioblastoma Multiforme

Inference of Subpathway Activity Profiles Reveals Metabolism Abnormal Subpathway Regions in Glioblastoma Multiforme

Glioblastoma, also known as glioblastoma multiforme (GBM), is the most malignant form of glioma and represents 81% of malignant brain and central nervous system (CNS) tumors. Like most cancers, GBM causes metabolic recombination to promote cell survival, proliferation, and invasion of cancer cells....

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Bibliographic Details
Main Authors: Xudong Han, Donghua Wang, Ping Zhao, Chonghui Liu, Yue Hao, Lulu Chang, Jiarui Zhao, Wei Zhao, Lili Mu, Jinghua Wang, Hulun Li, Qingfei Kong, Junwei Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
GBM
gene
metabolic subpathway
steroid biosynthesis
U87-MG cell
(S)-2,3-Epoxysqualene
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01549/full

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