Heterozygosis deficit of polymorphic markers linked to the β-globin gene cluster region in the Iranian population

Heterozygosis deficit of polymorphic markers linked to the β-globin gene cluster region in the Iranian population

Objective(s): Iran is considered as one of the high-prevalence areas for β-thalassemia with a rate of about 10% carrier frequency. Molecular diagnosis of the disease is performed both by direct sequencing and indirectly by the use of polymorphic markers present in the beta globin gene cluster. Howev...

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Bibliographic Details
Main Authors:	Tahereh Moradi, Reihaneh Vallian, Zahra Fazeli, Asieh Haghighatnia, Sadeq Vallian
Format:	Article
Language:	English
Published:	Mashhad University of Medical Sciences 2015-06-01
Series:	Iranian Journal of Basic Medical Sciences
Subjects:	β-globin gene cluster region β-thalassemia Iranian population Polymorphic markers
Online Access:	http://ijbms.mums.ac.ir/pdf_4531_889f2e4516bdf1d93d546cb91c183998.html

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