A Recognition-Molecule-Free Photoelectrochemical Sensor Based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> Heterostructure for Monitoring of Dopamine
Herein, a novel, recognition-molecule-free electrode based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> composites was synthesized using Ti<sub>3</sub>C<sub>2</sub> as the Ti source and TiO<sub>2</sub> in situ formed by oxidat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Biosensors |
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| Online Access: | https://www.mdpi.com/2079-6374/13/5/526 |
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| author | Zhifang Wu Fangjie Han Tianqi Wang Liwei Guan Zhishan Liang Dongxue Han Li Niu |
| author_facet | Zhifang Wu Fangjie Han Tianqi Wang Liwei Guan Zhishan Liang Dongxue Han Li Niu |
| author_sort | Zhifang Wu |
| collection | DOAJ |
| description | Herein, a novel, recognition-molecule-free electrode based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> composites was synthesized using Ti<sub>3</sub>C<sub>2</sub> as the Ti source and TiO<sub>2</sub> in situ formed by oxidation on the Ti<sub>3</sub>C<sub>2</sub> surface for the selective detection of dopamine (DA). The TiO<sub>2</sub> in situ formed by oxidation on the Ti<sub>3</sub>C<sub>2</sub> surface not only increased the catalytically active surface for DA binding but also accelerated the carrier transfer due to the coupling between TiO<sub>2</sub> and Ti<sub>3</sub>C<sub>2</sub>, resulting in a better photoelectric response than pure TiO<sub>2</sub>. Through a series of experimental conditions optimization, the photocurrent signals obtained by the MT100 electrode were proportional to the DA concentration from 0.125 to 400 µM, with a detection limit estimated at 0.045 µM. We also monitored DA in human blood serum samples using the MT100 electrode. The results showed good recovery, demonstrating the promising use of the sensor for the analysis of DA in real samples. |
| first_indexed | 2024-03-11T03:53:54Z |
| format | Article |
| id | doaj.art-8caf6792c94c422c9c252def5b4baba1 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-11T03:53:54Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-8caf6792c94c422c9c252def5b4baba12023-11-18T00:40:56ZengMDPI AGBiosensors2079-63742023-05-0113552610.3390/bios13050526A Recognition-Molecule-Free Photoelectrochemical Sensor Based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> Heterostructure for Monitoring of DopamineZhifang Wu0Fangjie Han1Tianqi Wang2Liwei Guan3Zhishan Liang4Dongxue Han5Li Niu6School of Economics and Statistics c/o Center for Advanced Analytical Science, c/o School of Chemistry and Chemical Engineering, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials and Devices, Guangzhou University, Guangzhou 510006, ChinaSchool of Economics and Statistics c/o Center for Advanced Analytical Science, c/o School of Chemistry and Chemical Engineering, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials and Devices, Guangzhou University, Guangzhou 510006, ChinaSchool of Economics and Statistics c/o Center for Advanced Analytical Science, c/o School of Chemistry and Chemical Engineering, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials and Devices, Guangzhou University, Guangzhou 510006, ChinaSchool of Economics and Statistics c/o Center for Advanced Analytical Science, c/o School of Chemistry and Chemical Engineering, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials and Devices, Guangzhou University, Guangzhou 510006, ChinaSchool of Economics and Statistics c/o Center for Advanced Analytical Science, c/o School of Chemistry and Chemical Engineering, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials and Devices, Guangzhou University, Guangzhou 510006, ChinaSchool of Economics and Statistics c/o Center for Advanced Analytical Science, c/o School of Chemistry and Chemical Engineering, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials and Devices, Guangzhou University, Guangzhou 510006, ChinaSchool of Economics and Statistics c/o Center for Advanced Analytical Science, c/o School of Chemistry and Chemical Engineering, Guangzhou Key Laboratory of Sensing Materials and Devices, Guangdong Engineering Technology Research Center for Photoelectric Sensing Materials and Devices, Guangzhou University, Guangzhou 510006, ChinaHerein, a novel, recognition-molecule-free electrode based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> composites was synthesized using Ti<sub>3</sub>C<sub>2</sub> as the Ti source and TiO<sub>2</sub> in situ formed by oxidation on the Ti<sub>3</sub>C<sub>2</sub> surface for the selective detection of dopamine (DA). The TiO<sub>2</sub> in situ formed by oxidation on the Ti<sub>3</sub>C<sub>2</sub> surface not only increased the catalytically active surface for DA binding but also accelerated the carrier transfer due to the coupling between TiO<sub>2</sub> and Ti<sub>3</sub>C<sub>2</sub>, resulting in a better photoelectric response than pure TiO<sub>2</sub>. Through a series of experimental conditions optimization, the photocurrent signals obtained by the MT100 electrode were proportional to the DA concentration from 0.125 to 400 µM, with a detection limit estimated at 0.045 µM. We also monitored DA in human blood serum samples using the MT100 electrode. The results showed good recovery, demonstrating the promising use of the sensor for the analysis of DA in real samples.https://www.mdpi.com/2079-6374/13/5/526photoelectrochemicalMXenedopamine sensor |
| spellingShingle | Zhifang Wu Fangjie Han Tianqi Wang Liwei Guan Zhishan Liang Dongxue Han Li Niu A Recognition-Molecule-Free Photoelectrochemical Sensor Based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> Heterostructure for Monitoring of Dopamine Biosensors photoelectrochemical MXene dopamine sensor |
| title | A Recognition-Molecule-Free Photoelectrochemical Sensor Based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> Heterostructure for Monitoring of Dopamine |
| title_full | A Recognition-Molecule-Free Photoelectrochemical Sensor Based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> Heterostructure for Monitoring of Dopamine |
| title_fullStr | A Recognition-Molecule-Free Photoelectrochemical Sensor Based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> Heterostructure for Monitoring of Dopamine |
| title_full_unstemmed | A Recognition-Molecule-Free Photoelectrochemical Sensor Based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> Heterostructure for Monitoring of Dopamine |
| title_short | A Recognition-Molecule-Free Photoelectrochemical Sensor Based on Ti<sub>3</sub>C<sub>2</sub>/TiO<sub>2</sub> Heterostructure for Monitoring of Dopamine |
| title_sort | recognition molecule free photoelectrochemical sensor based on ti sub 3 sub c sub 2 sub tio sub 2 sub heterostructure for monitoring of dopamine |
| topic | photoelectrochemical MXene dopamine sensor |
| url | https://www.mdpi.com/2079-6374/13/5/526 |
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