Stem Cell Therapy for Diabetic Foot Ulcers: Theory and Practice
Diabetic foot ulcers are associated with increases in limb amputation, morbidity, and mortality. Recently, a stem cell application is emerging as promising adjuvant therapy. We presented available remedies by conducting a literature review on the application, safety, and efficacy of stem cell therap...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2022-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2022/6028743 |
| _version_ | 1797980380543844352 |
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| author | David Lubasi Nalisa Md. Moneruzzaman Geoffrey J. Changwe Youchaou Mobet Li Ping Li Yu Jin Ma Hong Wei Jiang |
| author_facet | David Lubasi Nalisa Md. Moneruzzaman Geoffrey J. Changwe Youchaou Mobet Li Ping Li Yu Jin Ma Hong Wei Jiang |
| author_sort | David Lubasi Nalisa |
| collection | DOAJ |
| description | Diabetic foot ulcers are associated with increases in limb amputation, morbidity, and mortality. Recently, a stem cell application is emerging as promising adjuvant therapy. We presented available remedies by conducting a literature review on the application, safety, and efficacy of stem cell therapy. Relevant literature, including randomized control trials and article journals, was obtained from reputable search engines (PubMed, Scopus, and Web of Science). We analyzed five credible cohorts, with variable sources of stem cells, in a total of 216 participants, 151 males and 65 females, age (mean±SD) of 64.5±9.6 years. With an average success of 86.41% in all Wagner-II lesions, mesenchymal SCA (stem cell application) is safe and effective, hence can significantly prevent limb amputation. |
| first_indexed | 2024-04-11T05:54:31Z |
| format | Article |
| id | doaj.art-8cb16626b5484b73b8c3bd2f5526d7a8 |
| institution | Directory Open Access Journal |
| issn | 2314-6753 |
| language | English |
| last_indexed | 2024-04-11T05:54:31Z |
| publishDate | 2022-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj.art-8cb16626b5484b73b8c3bd2f5526d7a82022-12-22T04:41:58ZengHindawi LimitedJournal of Diabetes Research2314-67532022-01-01202210.1155/2022/6028743Stem Cell Therapy for Diabetic Foot Ulcers: Theory and PracticeDavid Lubasi Nalisa0Md. Moneruzzaman1Geoffrey J. Changwe2Youchaou Mobet3Li Ping Li4Yu Jin Ma5Hong Wei Jiang6Department of Metabolism and EndocrinologyDepartment of Rehabilitation Medicine and PhysiotherapyDepartment of Cardiovascular and Thoracic SurgeryDepartment of Obstetrics and GynecologyDepartment of Metabolism and EndocrinologyDepartment of Metabolism and EndocrinologyDepartment of Metabolism and EndocrinologyDiabetic foot ulcers are associated with increases in limb amputation, morbidity, and mortality. Recently, a stem cell application is emerging as promising adjuvant therapy. We presented available remedies by conducting a literature review on the application, safety, and efficacy of stem cell therapy. Relevant literature, including randomized control trials and article journals, was obtained from reputable search engines (PubMed, Scopus, and Web of Science). We analyzed five credible cohorts, with variable sources of stem cells, in a total of 216 participants, 151 males and 65 females, age (mean±SD) of 64.5±9.6 years. With an average success of 86.41% in all Wagner-II lesions, mesenchymal SCA (stem cell application) is safe and effective, hence can significantly prevent limb amputation.http://dx.doi.org/10.1155/2022/6028743 |
| spellingShingle | David Lubasi Nalisa Md. Moneruzzaman Geoffrey J. Changwe Youchaou Mobet Li Ping Li Yu Jin Ma Hong Wei Jiang Stem Cell Therapy for Diabetic Foot Ulcers: Theory and Practice Journal of Diabetes Research |
| title | Stem Cell Therapy for Diabetic Foot Ulcers: Theory and Practice |
| title_full | Stem Cell Therapy for Diabetic Foot Ulcers: Theory and Practice |
| title_fullStr | Stem Cell Therapy for Diabetic Foot Ulcers: Theory and Practice |
| title_full_unstemmed | Stem Cell Therapy for Diabetic Foot Ulcers: Theory and Practice |
| title_short | Stem Cell Therapy for Diabetic Foot Ulcers: Theory and Practice |
| title_sort | stem cell therapy for diabetic foot ulcers theory and practice |
| url | http://dx.doi.org/10.1155/2022/6028743 |
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