The efficacy of midline catheters—a prospective, randomized, active-controlled study
Objectives: This study was performed to investigate whether an intravenous (IV) strategy based on new-generation midline catheters is an efficacious alternative to a conventional IV strategy consisting of peripheral venous catheters and central venous catheters, for patients needing IV therapy excee...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | International Journal of Infectious Diseases |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971220322578 |
| _version_ | 1818665746713018368 |
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| author | Emma Bundgaard Nielsen Louise Antonsen Camilla Mensel Nikolaj Milandt Lars Skov Dalgaard Britta Skov Illum Hanne Arildsen Peter Juhl-Olsen |
| author_facet | Emma Bundgaard Nielsen Louise Antonsen Camilla Mensel Nikolaj Milandt Lars Skov Dalgaard Britta Skov Illum Hanne Arildsen Peter Juhl-Olsen |
| author_sort | Emma Bundgaard Nielsen |
| collection | DOAJ |
| description | Objectives: This study was performed to investigate whether an intravenous (IV) strategy based on new-generation midline catheters is an efficacious alternative to a conventional IV strategy consisting of peripheral venous catheters and central venous catheters, for patients needing IV therapy exceeding 5 days. Methods: This was a prospective, randomized, controlled study. Patients requiring more than 5 days of IV treatment were randomized to either a midline catheter-based IV strategy or a conventional strategy. The primary endpoint was the composite of the insertion of a central venous catheter (CVC) or the need for four or more peripheral venous catheter (PVC) insertions. The secondary outcomes included catheter dwell times and reasons for premature removal. Results: One hundred and twenty patients were included. The fraction of patients receiving four or more PVCs or having a CVC inserted was 12/58 (21%) in the midline group versus 38/58 (66%) in the conventional group (p < 0.001); the number needed to treat was 2.2. The median overall catheter dwell time was 7 days (range 0–60 days) in the midline group and 4 days (range 0–84 days) in the conventional group (p = 0.002). Conclusion: In patients requiring more than 5 days of IV therapy, a midline catheter strategy reduced the need for insertion of a CVC or four or more PVCs. |
| first_indexed | 2024-12-17T05:53:32Z |
| format | Article |
| id | doaj.art-8cb1b643632b4e7ab5cc1453057bccb2 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-12-17T05:53:32Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-8cb1b643632b4e7ab5cc1453057bccb22022-12-21T22:01:06ZengElsevierInternational Journal of Infectious Diseases1201-97122021-01-01102220225The efficacy of midline catheters—a prospective, randomized, active-controlled studyEmma Bundgaard Nielsen0Louise Antonsen1Camilla Mensel2Nikolaj Milandt3Lars Skov Dalgaard4Britta Skov Illum5Hanne Arildsen6Peter Juhl-Olsen7Department of Anesthesiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, DenmarkDepartment of Anesthesiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, DenmarkDepartment of Anesthesiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, DenmarkDepartment of Anesthesiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, DenmarkDepartment of Medicine, The Regional Hospital West Jutland, Gl. Landevej 72, 7400 Herning, DenmarkDepartment of Anesthesiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, DenmarkDepartment of Infectious Diseases, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, DenmarkDepartment of Anesthesiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark; Institute for Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 82, 8200 Aarhus N, Denmark; Corresponding author at: Department of Anaesthesiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark.Objectives: This study was performed to investigate whether an intravenous (IV) strategy based on new-generation midline catheters is an efficacious alternative to a conventional IV strategy consisting of peripheral venous catheters and central venous catheters, for patients needing IV therapy exceeding 5 days. Methods: This was a prospective, randomized, controlled study. Patients requiring more than 5 days of IV treatment were randomized to either a midline catheter-based IV strategy or a conventional strategy. The primary endpoint was the composite of the insertion of a central venous catheter (CVC) or the need for four or more peripheral venous catheter (PVC) insertions. The secondary outcomes included catheter dwell times and reasons for premature removal. Results: One hundred and twenty patients were included. The fraction of patients receiving four or more PVCs or having a CVC inserted was 12/58 (21%) in the midline group versus 38/58 (66%) in the conventional group (p < 0.001); the number needed to treat was 2.2. The median overall catheter dwell time was 7 days (range 0–60 days) in the midline group and 4 days (range 0–84 days) in the conventional group (p = 0.002). Conclusion: In patients requiring more than 5 days of IV therapy, a midline catheter strategy reduced the need for insertion of a CVC or four or more PVCs.http://www.sciencedirect.com/science/article/pii/S1201971220322578Midline catheterIntravenous catheterPICCIntravenous therapy |
| spellingShingle | Emma Bundgaard Nielsen Louise Antonsen Camilla Mensel Nikolaj Milandt Lars Skov Dalgaard Britta Skov Illum Hanne Arildsen Peter Juhl-Olsen The efficacy of midline catheters—a prospective, randomized, active-controlled study International Journal of Infectious Diseases Midline catheter Intravenous catheter PICC Intravenous therapy |
| title | The efficacy of midline catheters—a prospective, randomized, active-controlled study |
| title_full | The efficacy of midline catheters—a prospective, randomized, active-controlled study |
| title_fullStr | The efficacy of midline catheters—a prospective, randomized, active-controlled study |
| title_full_unstemmed | The efficacy of midline catheters—a prospective, randomized, active-controlled study |
| title_short | The efficacy of midline catheters—a prospective, randomized, active-controlled study |
| title_sort | efficacy of midline catheters a prospective randomized active controlled study |
| topic | Midline catheter Intravenous catheter PICC Intravenous therapy |
| url | http://www.sciencedirect.com/science/article/pii/S1201971220322578 |
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