Green synthesis of Ag/Fe3O4 nanoparticles using Mentha longifolia flower extract: evaluation of its antioxidant and anti-lung cancer effects
Herein, a bio-inspired synthetic method for Ag NP adorned biofunctionalized magnetic nanocomposite has been demonstrated. In the procedure, Mentha longifolia flower extract was employed as a template for the green reduction of immobilized Ag ions to corresponding NPs and subsequent stabilization. Th...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844022036143 |
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| author | Lei Wang Bikash Karmakar Fatimah A. Al-Saeed Ali A. ٍShati Mutasem Z. Bani-Fwaz Attalla F. El-kott |
| author_facet | Lei Wang Bikash Karmakar Fatimah A. Al-Saeed Ali A. ٍShati Mutasem Z. Bani-Fwaz Attalla F. El-kott |
| author_sort | Lei Wang |
| collection | DOAJ |
| description | Herein, a bio-inspired synthetic method for Ag NP adorned biofunctionalized magnetic nanocomposite has been demonstrated. In the procedure, Mentha longifolia flower extract was employed as a template for the green reduction of immobilized Ag ions to corresponding NPs and subsequent stabilization. The phytochemical modification also facilitated the Fe3O4 NPs to protect from self-aggregation. The as-synthesized Ag/Fe3O4 nanocomposite material was characterized by SEM, TEM, EDX, elemental mapping, VSM, XRD and ICP-OES methods. Towards the biological application, the material was first explored in the anti-oxidant study following DPPH assay and it exhibited a significant radical scavenging capacity. The application of Ag/Fe3O4 nanocomposite was further progressed in the anticancer study against standard human lung cancer cell lines (A549 and H358). Cytotoxicity of the material against the cell lines were determined in terms of % cell viability following MTT method and was found to decrease with increase in the material load. |
| first_indexed | 2024-04-11T00:51:18Z |
| format | Article |
| id | doaj.art-8cb586af0a51479d83bfe9751061d1e8 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-11T00:51:18Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-8cb586af0a51479d83bfe9751061d1e82023-01-05T08:39:56ZengElsevierHeliyon2405-84402022-12-01812e12326Green synthesis of Ag/Fe3O4 nanoparticles using Mentha longifolia flower extract: evaluation of its antioxidant and anti-lung cancer effectsLei Wang0Bikash Karmakar1Fatimah A. Al-Saeed2Ali A. ٍShati3Mutasem Z. Bani-Fwaz4Attalla F. El-kott5Department of Respiratory and Critical Care Medicine, Tianjin Chest Hospital, Tianjin City, 300222, ChinaDepartment of Chemistry, Gobardanga Hindu College, 24 Parganas (North), India; Corresponding author.Department of Biology, College of Science, King Khalid University, Abha, 61421, Saudi ArabiaDepartment of Biology, College of Science, King Khalid University, Abha, 61421, Saudi ArabiaDepartment of Chemistry, College of Science, King Khalid University, P. O. Box 9004, Abha, 61413, Saudi ArabiaDepartment of Biology, College of Science, King Khalid University, Abha, 61421, Saudi Arabia; Department of Zoology, Faculty of Science, Damanhour University, Damanhour, 22511, EgyptHerein, a bio-inspired synthetic method for Ag NP adorned biofunctionalized magnetic nanocomposite has been demonstrated. In the procedure, Mentha longifolia flower extract was employed as a template for the green reduction of immobilized Ag ions to corresponding NPs and subsequent stabilization. The phytochemical modification also facilitated the Fe3O4 NPs to protect from self-aggregation. The as-synthesized Ag/Fe3O4 nanocomposite material was characterized by SEM, TEM, EDX, elemental mapping, VSM, XRD and ICP-OES methods. Towards the biological application, the material was first explored in the anti-oxidant study following DPPH assay and it exhibited a significant radical scavenging capacity. The application of Ag/Fe3O4 nanocomposite was further progressed in the anticancer study against standard human lung cancer cell lines (A549 and H358). Cytotoxicity of the material against the cell lines were determined in terms of % cell viability following MTT method and was found to decrease with increase in the material load.http://www.sciencedirect.com/science/article/pii/S2405844022036143Ag nanoparticlesMagnetic nanocompositeGreen synthesisLug cancer |
| spellingShingle | Lei Wang Bikash Karmakar Fatimah A. Al-Saeed Ali A. ٍShati Mutasem Z. Bani-Fwaz Attalla F. El-kott Green synthesis of Ag/Fe3O4 nanoparticles using Mentha longifolia flower extract: evaluation of its antioxidant and anti-lung cancer effects Heliyon Ag nanoparticles Magnetic nanocomposite Green synthesis Lug cancer |
| title | Green synthesis of Ag/Fe3O4 nanoparticles using Mentha longifolia flower extract: evaluation of its antioxidant and anti-lung cancer effects |
| title_full | Green synthesis of Ag/Fe3O4 nanoparticles using Mentha longifolia flower extract: evaluation of its antioxidant and anti-lung cancer effects |
| title_fullStr | Green synthesis of Ag/Fe3O4 nanoparticles using Mentha longifolia flower extract: evaluation of its antioxidant and anti-lung cancer effects |
| title_full_unstemmed | Green synthesis of Ag/Fe3O4 nanoparticles using Mentha longifolia flower extract: evaluation of its antioxidant and anti-lung cancer effects |
| title_short | Green synthesis of Ag/Fe3O4 nanoparticles using Mentha longifolia flower extract: evaluation of its antioxidant and anti-lung cancer effects |
| title_sort | green synthesis of ag fe3o4 nanoparticles using mentha longifolia flower extract evaluation of its antioxidant and anti lung cancer effects |
| topic | Ag nanoparticles Magnetic nanocomposite Green synthesis Lug cancer |
| url | http://www.sciencedirect.com/science/article/pii/S2405844022036143 |
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