Astrocyte derived TSP2 contributes to synaptic alteration and visual dysfunction in retinal ischemia/reperfusion injury

Astrocyte derived TSP2 contributes to synaptic alteration and visual dysfunction in retinal ischemia/reperfusion injury

Abstract Background Despite current intervention measures/therapies are able to ameliorate neuronal death following retinal injuries/diseases, the recovery of visual function remains unsatisfactory. Previous studies revealed that the retinal synapse and neurite changed during the early stage after r...

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Bibliographic Details
Main Authors: Tu Hu, Shuhan Meng, Qianyue Zhang, Shuang Song, Cheng Tan, Jufang Huang, Dan Chen
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Cell & Bioscience
Subjects:
Retinal ischemia/reperfusion
Axons
Compensatory synaptic remodeling
Visual dysfunction
Astrocyte
Thrombospondin 2
Online Access:https://doi.org/10.1186/s13578-022-00932-1

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