Tetraciclinas e glicilciclinas: uma visão geral Tetracyclines and glycylcyclines: an overview
<abstract language="eng">Tetracyclines exhibits activity to a broad range of Gram-negative and Gram-positive bacteria and this fact allied to the low toxicity, low cost, and the advantage of administration by oral route led to their indiscriminate use, which caused the appearance of...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Química
2010-01-01
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| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000300038 |
| _version_ | 1819168907640963072 |
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| author | Elene Cristina Pereira-Maia Priscila Pereira Silva Wagner Batista de Almeida Hélio Ferreira dos Santos Bruna Luana Marcial Reinaldo Ruggiero Wendell Guerra |
| author_facet | Elene Cristina Pereira-Maia Priscila Pereira Silva Wagner Batista de Almeida Hélio Ferreira dos Santos Bruna Luana Marcial Reinaldo Ruggiero Wendell Guerra |
| author_sort | Elene Cristina Pereira-Maia |
| collection | DOAJ |
| description | <abstract language="eng">Tetracyclines exhibits activity to a broad range of Gram-negative and Gram-positive bacteria and this fact allied to the low toxicity, low cost, and the advantage of administration by oral route led to their indiscriminate use, which caused the appearance of bacterial resistance to these agents, wich has restricted its clinical utility, though new applications have emerged. On the other hand, the glycylcyclines, semi-synthetic products are similar to tetracyclines, which are active against many bacteria resistant to tetracycline and other classes of antibiotics. The purpose of this paper is to give an overview of this important class of antibiotics focusing on its coordination chemistry and possible applications. |
| first_indexed | 2024-12-22T19:11:04Z |
| format | Article |
| id | doaj.art-8cb87ec1efbe45b3aeacbac77fd64eab |
| institution | Directory Open Access Journal |
| issn | 0100-4042 1678-7064 |
| language | English |
| last_indexed | 2024-12-22T19:11:04Z |
| publishDate | 2010-01-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-8cb87ec1efbe45b3aeacbac77fd64eab2022-12-21T18:15:40ZengSociedade Brasileira de QuímicaQuímica Nova0100-40421678-70642010-01-0133370070610.1590/S0100-40422010000300038Tetraciclinas e glicilciclinas: uma visão geral Tetracyclines and glycylcyclines: an overviewElene Cristina Pereira-MaiaPriscila Pereira SilvaWagner Batista de AlmeidaHélio Ferreira dos SantosBruna Luana MarcialReinaldo RuggieroWendell Guerra<abstract language="eng">Tetracyclines exhibits activity to a broad range of Gram-negative and Gram-positive bacteria and this fact allied to the low toxicity, low cost, and the advantage of administration by oral route led to their indiscriminate use, which caused the appearance of bacterial resistance to these agents, wich has restricted its clinical utility, though new applications have emerged. On the other hand, the glycylcyclines, semi-synthetic products are similar to tetracyclines, which are active against many bacteria resistant to tetracycline and other classes of antibiotics. The purpose of this paper is to give an overview of this important class of antibiotics focusing on its coordination chemistry and possible applications.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000300038tetracyclinesglycylcyclinesantibacterial activity |
| spellingShingle | Elene Cristina Pereira-Maia Priscila Pereira Silva Wagner Batista de Almeida Hélio Ferreira dos Santos Bruna Luana Marcial Reinaldo Ruggiero Wendell Guerra Tetraciclinas e glicilciclinas: uma visão geral Tetracyclines and glycylcyclines: an overview Química Nova tetracyclines glycylcyclines antibacterial activity |
| title | Tetraciclinas e glicilciclinas: uma visão geral Tetracyclines and glycylcyclines: an overview |
| title_full | Tetraciclinas e glicilciclinas: uma visão geral Tetracyclines and glycylcyclines: an overview |
| title_fullStr | Tetraciclinas e glicilciclinas: uma visão geral Tetracyclines and glycylcyclines: an overview |
| title_full_unstemmed | Tetraciclinas e glicilciclinas: uma visão geral Tetracyclines and glycylcyclines: an overview |
| title_short | Tetraciclinas e glicilciclinas: uma visão geral Tetracyclines and glycylcyclines: an overview |
| title_sort | tetraciclinas e glicilciclinas uma visao geral tetracyclines and glycylcyclines an overview |
| topic | tetracyclines glycylcyclines antibacterial activity |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422010000300038 |
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