Computational Tools to Assist in Analyzing Effects of the <i>SERPINA1</i> Gene Variation on Alpha-1 Antitrypsin (AAT)
In the rapidly advancing field of bioinformatics, the development and application of computational tools to predict the effects of single nucleotide variants (SNVs) are shedding light on the molecular mechanisms underlying disorders. Also, they hold promise for guiding therapeutic interventions and...
Main Authors: | Jakub Mróz, Magdalena Pelc, Karolina Mitusińska, Joanna Chorostowska-Wynimko, Aleksandra Jezela-Stanek |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2024-03-01
|
Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/15/3/340 |
Similar Items
-
<i>SERPINA1</i> and More? A Putative Genetic Contributor to Pulmonary Dysfunction in Alpha-1 Antitrypsin Deficiency
by: Aleksandra Jezela-Stanek, et al.
Published: (2023-02-01) -
Rare variants in alpha 1 antitrypsin deficiency: a systematic literature review
by: Ilaria Ferrarotti, et al.
Published: (2024-02-01) -
Post-Translational Modifications of Circulating Alpha-1-Antitrypsin Protein
by: Urszula Lechowicz, et al.
Published: (2020-12-01) -
Clinical Significance of <i>SERPINA1</i> Gene and Its Encoded Alpha1-antitrypsin Protein in NSCLC
by: Evrim Ercetin, et al.
Published: (2019-09-01) -
Alpha-1 Antitrypsin and Hepatocellular Carcinoma in Liver Cirrhosis: <i>SERPINA1</i> MZ or MS Genotype Carriage Decreases the Risk
by: Zuzana Rabekova, et al.
Published: (2021-09-01)