Is the 4-factor model of symptomology equivalent across bipolar disorder subtypes?

Abstract Background Research with the BDSx (Bipolar Disorder Symptom Scale) suggests a 4-factor structure of responses: two depression (cognitive, somatic) and two hypo/mania factors (elation/loss of insight, affrontive symptoms). The two depression and two hypo/mania factors are correlated; and aff...

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Main Authors: Norm O’Rourke, Andrew Sixsmith, Tal Michael, Yaacov G. Bachner
Format: Article
Language:English
Published: SpringerOpen 2021-08-01
Series:International Journal of Bipolar Disorders
Subjects:
Online Access:https://doi.org/10.1186/s40345-021-00229-1
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author Norm O’Rourke
Andrew Sixsmith
Tal Michael
Yaacov G. Bachner
author_facet Norm O’Rourke
Andrew Sixsmith
Tal Michael
Yaacov G. Bachner
author_sort Norm O’Rourke
collection DOAJ
description Abstract Background Research with the BDSx (Bipolar Disorder Symptom Scale) suggests a 4-factor structure of responses: two depression (cognitive, somatic) and two hypo/mania factors (elation/loss of insight, affrontive symptoms). The two depression and two hypo/mania factors are correlated; and affrontive symptoms of hypo/mania (e.g., furious, disgusted, argumentative) are positively correlated with both depression factors suggesting pathways for mixed symptom presentation. This grouping of affrontive symptoms of hypo/mania organically emerged in exploratory research and has subsequently been supported in confirmatory analyses between samples and over time. The BDSx has been clinically validated with BD outpatients. Results Over 19 days, we recruited an international sample of 784 adults with BD using micro-targeted, social media advertising (M  =  44.48 years, range 18–82). All participants indicated that they had BD (subtype, if known) and had been diagnosed with BD (month, year). This sample size was sufficient to confirm the 4-factor model across subtypes and compare the three (BD I, BD II, BD NOS). Responses to 19 of 20 BDSx items were psychometrically consistent across BD subtypes. Only responses to the ‘hopeless’ item were significantly higher for those with BD II. Conclusions When comparing models, it appears that affrontive symptoms are significantly and uniformly associated with hypo/mania and both depression factors across subtypes. In contrast to BD diagnostic criteria, this suggests that affrontive symptoms are central to the clinical presentation of hypo/mania and mixed symptomology across BD subtypes.
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spelling doaj.art-8cbbb5656f1c425982b090b4bebc8a042022-12-21T20:40:48ZengSpringerOpenInternational Journal of Bipolar Disorders2194-75112021-08-01911910.1186/s40345-021-00229-1Is the 4-factor model of symptomology equivalent across bipolar disorder subtypes?Norm O’Rourke0Andrew Sixsmith1Tal Michael2Yaacov G. Bachner3Department of Public Health and Multidisciplinary Center for Research On Aging, Ben-Gurion University of the NegevSTAR Institute, Simon Fraser UniversitySchool of Public Health, Faculty of Health Sciences, Ben-Gurion University of the NegevDepartment of Public Health and Multidisciplinary Center for Research On Aging, Ben-Gurion University of the NegevAbstract Background Research with the BDSx (Bipolar Disorder Symptom Scale) suggests a 4-factor structure of responses: two depression (cognitive, somatic) and two hypo/mania factors (elation/loss of insight, affrontive symptoms). The two depression and two hypo/mania factors are correlated; and affrontive symptoms of hypo/mania (e.g., furious, disgusted, argumentative) are positively correlated with both depression factors suggesting pathways for mixed symptom presentation. This grouping of affrontive symptoms of hypo/mania organically emerged in exploratory research and has subsequently been supported in confirmatory analyses between samples and over time. The BDSx has been clinically validated with BD outpatients. Results Over 19 days, we recruited an international sample of 784 adults with BD using micro-targeted, social media advertising (M  =  44.48 years, range 18–82). All participants indicated that they had BD (subtype, if known) and had been diagnosed with BD (month, year). This sample size was sufficient to confirm the 4-factor model across subtypes and compare the three (BD I, BD II, BD NOS). Responses to 19 of 20 BDSx items were psychometrically consistent across BD subtypes. Only responses to the ‘hopeless’ item were significantly higher for those with BD II. Conclusions When comparing models, it appears that affrontive symptoms are significantly and uniformly associated with hypo/mania and both depression factors across subtypes. In contrast to BD diagnostic criteria, this suggests that affrontive symptoms are central to the clinical presentation of hypo/mania and mixed symptomology across BD subtypes.https://doi.org/10.1186/s40345-021-00229-1Affrontive symptomsBDSxBipolar disorderBD subtypesInvariance analysesScale validation
spellingShingle Norm O’Rourke
Andrew Sixsmith
Tal Michael
Yaacov G. Bachner
Is the 4-factor model of symptomology equivalent across bipolar disorder subtypes?
International Journal of Bipolar Disorders
Affrontive symptoms
BDSx
Bipolar disorder
BD subtypes
Invariance analyses
Scale validation
title Is the 4-factor model of symptomology equivalent across bipolar disorder subtypes?
title_full Is the 4-factor model of symptomology equivalent across bipolar disorder subtypes?
title_fullStr Is the 4-factor model of symptomology equivalent across bipolar disorder subtypes?
title_full_unstemmed Is the 4-factor model of symptomology equivalent across bipolar disorder subtypes?
title_short Is the 4-factor model of symptomology equivalent across bipolar disorder subtypes?
title_sort is the 4 factor model of symptomology equivalent across bipolar disorder subtypes
topic Affrontive symptoms
BDSx
Bipolar disorder
BD subtypes
Invariance analyses
Scale validation
url https://doi.org/10.1186/s40345-021-00229-1
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