Use of Half-Generation PAMAM Dendrimers (G0.5–G3.5) with Carboxylate End-Groups to Improve the DACHPtCl<sub>2</sub> and 5-FU Efficacy as Anticancer Drugs

The DACHPtCl<sub>2</sub> compound (<i>trans</i>-(R,R)-1,2-diaminocyclohexanedichloroplatinum(II)) is a potent anticancer drug with a broad spectrum of activity and is less toxic than oxaliplatin (<i>trans</i>-l-diaminocyclohexane oxalate platinum II), with which i...

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Bibliographic Details
Main Authors: Cláudia Camacho, Helena Tomás, João Rodrigues
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/10/2924

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