Glucose-Lowering Effects of Imeglimin and Its Possible Beneficial Effects on Diabetic Complications

Glucose-Lowering Effects of Imeglimin and Its Possible Beneficial Effects on Diabetic Complications

Mitochondrial dysfunction is a prominent pathological feature of type 2 diabetes, which contributes to β-cell mass reduction and insulin resistance. Imeglimin is a novel oral hypoglycemic agent with a unique mechanism of action targeting mitochondrial bioenergetics. Imeglimin reduces reactive oxygen...

Full description

Bibliographic Details
Main Authors: Hidekatsu Yanai, Hiroki Adachi, Mariko Hakoshima, Hisayuki Katsuyama
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Biology
Subjects:
β-cell
endoplasmic reticulum
glucose-stimulated insulin secretion
imeglimin
mitochondria
Online Access:https://www.mdpi.com/2079-7737/12/5/726

Similar Items

Similar Items