Segmental Arterial Mediolysis: A Case Study and Review of the Literature in Accurate Diagnosis and Management

Segmental arterial mediolysis (SAM) is a rare noninflammatory, nonarteriosclerotic arteriopathy of an unknown etiology. It most commonly affects the medium-sized vessels of the abdomen and is characterized by the disruption of the arterial medial layer. Although histological confirmation remains the...

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Main Author: Rebekah Tan
Format: Article
Language:English
Published: Medrang 2019-09-01
Series:Vascular Specialist International
Subjects:
Online Access:http://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.2019.35.3.174
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author Rebekah Tan
author_facet Rebekah Tan
author_sort Rebekah Tan
collection DOAJ
description Segmental arterial mediolysis (SAM) is a rare noninflammatory, nonarteriosclerotic arteriopathy of an unknown etiology. It most commonly affects the medium-sized vessels of the abdomen and is characterized by the disruption of the arterial medial layer. Although histological confirmation remains the gold standard in diagnosis, the use of computed tomography angiography (CTA) has greatly aided the diagnosis and surveillance of SAM. Given its rarity and angiographic similarities to other vasculopathies, the diagnosis of SAM can be challenging and is often missed. We describe the case of a 46-year-old male patient who presented to our institution with abdominal pain and multiple foci of intra-abdominal arterial dissections on CTA. We report the acute management via endovascular intervention and review the literature with respect to the diagnosis and management of this rare condition. SAM remains an uncommon yet significant disease process requiring prompt and accurate diagnosis. Initiation of immediate treatment is crucial, given the knowledge gap about its natural progression.
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spelling doaj.art-8cc05c41a14d4392b42b498e6a607e462022-12-22T00:38:13ZengMedrangVascular Specialist International2288-79702019-09-0135317417910.5758/vsi.2019.35.3.174vsi.2019.35.3.174Segmental Arterial Mediolysis: A Case Study and Review of the Literature in Accurate Diagnosis and ManagementRebekah Tan0Department of Vascular Surgery, Sir Charles Gairdner Hospital, Nedlands, AustraliaSegmental arterial mediolysis (SAM) is a rare noninflammatory, nonarteriosclerotic arteriopathy of an unknown etiology. It most commonly affects the medium-sized vessels of the abdomen and is characterized by the disruption of the arterial medial layer. Although histological confirmation remains the gold standard in diagnosis, the use of computed tomography angiography (CTA) has greatly aided the diagnosis and surveillance of SAM. Given its rarity and angiographic similarities to other vasculopathies, the diagnosis of SAM can be challenging and is often missed. We describe the case of a 46-year-old male patient who presented to our institution with abdominal pain and multiple foci of intra-abdominal arterial dissections on CTA. We report the acute management via endovascular intervention and review the literature with respect to the diagnosis and management of this rare condition. SAM remains an uncommon yet significant disease process requiring prompt and accurate diagnosis. Initiation of immediate treatment is crucial, given the knowledge gap about its natural progression.http://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.2019.35.3.174Segmental arterial mediolysisEndovascularDissection
spellingShingle Rebekah Tan
Segmental Arterial Mediolysis: A Case Study and Review of the Literature in Accurate Diagnosis and Management
Vascular Specialist International
Segmental arterial mediolysis
Endovascular
Dissection
title Segmental Arterial Mediolysis: A Case Study and Review of the Literature in Accurate Diagnosis and Management
title_full Segmental Arterial Mediolysis: A Case Study and Review of the Literature in Accurate Diagnosis and Management
title_fullStr Segmental Arterial Mediolysis: A Case Study and Review of the Literature in Accurate Diagnosis and Management
title_full_unstemmed Segmental Arterial Mediolysis: A Case Study and Review of the Literature in Accurate Diagnosis and Management
title_short Segmental Arterial Mediolysis: A Case Study and Review of the Literature in Accurate Diagnosis and Management
title_sort segmental arterial mediolysis a case study and review of the literature in accurate diagnosis and management
topic Segmental arterial mediolysis
Endovascular
Dissection
url http://www.vsijournal.org/journal/view.html?doi=10.5758/vsi.2019.35.3.174
work_keys_str_mv AT rebekahtan segmentalarterialmediolysisacasestudyandreviewoftheliteratureinaccuratediagnosisandmanagement