Pharmacokinetics and Safety of WHO-Recommended Dosage and Higher Dosage of Levofloxacin for Tuberculosis Treatment in Children: a Pilot Study

Pharmacokinetics and Safety of WHO-Recommended Dosage and Higher Dosage of Levofloxacin for Tuberculosis Treatment in Children: a Pilot Study

Objectives: To evaluate the pharmacokinetic parameters of the 2020 World Health Organization (WHO)-recommended pediatric dosage of levofloxacin and the higher-than-WHO dosage. Methods: Children aged 1-15 years with tuberculosis who received levofloxacin-based treatment for at least 7 days were enrol...

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Bibliographic Details
Main Authors: Watsamon Jantarabenjakul, Piyarat Suntarattiwong, Noppadol Wacharachaisurapol, Praon Supradish Na Ayudhya, Weeraya Phaisal, Monta Tawan, Juthamanee Moonwong, Tavitiya Sudjaritruk, Pajaree Chariyavilaskul, Thanyawee Puthanakit
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:International Journal of Infectious Diseases
Subjects:
Levofloxacin
Isoniazid-resistant tuberculosis
Drug-resistant tuberculosis
Pharmacokinetics
Children
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971222004258

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