The scientific basis of rasa (taste) of a substance as a tool to explore its pharmacological behavior

Background: A rational and well-developed pharmacological basis forms the foundation of therapeutics in Ayurveda. The principles and theories of Ayurveda need to be validated in the scientific context in order to harness the millennia old knowledge. Rasa (taste) of the substance is the foremost tool...

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Main Authors: Sudipta Kumar Rath, Asit Kumar Panja, Lalit Nagar, Ashashri Shinde
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Ancient Science of Life
Subjects:
Online Access:http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2014;volume=33;issue=4;spage=198;epage=202;aulast=Rath
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author Sudipta Kumar Rath
Asit Kumar Panja
Lalit Nagar
Ashashri Shinde
author_facet Sudipta Kumar Rath
Asit Kumar Panja
Lalit Nagar
Ashashri Shinde
author_sort Sudipta Kumar Rath
collection DOAJ
description Background: A rational and well-developed pharmacological basis forms the foundation of therapeutics in Ayurveda. The principles and theories of Ayurveda need to be validated in the scientific context in order to harness the millennia old knowledge. Rasa (taste) of the substance is the foremost tool in Ayurveda to assess and determine the pharmacological properties and actions of the substance. Similarity in rasa is said to signify similar structure and consequently similar pharmacological behavior. Depending on skills developed over the course of long-term clinical experience one, can register the minute variations in rasa of substances and accordingly the possible variations in pharmacological actions. Thus, rasa can be used as a scientific tool in the drug discovery process to limit and focus the target areas. Aim: To sensitize scientific community to the utility of rasa as a tool in the process of drug discovery. Materials and Methods: All relevant ancient and contemporary literature was reviewed critically to form a scientific basis of the Ayurvedic concept of rasa as a tool to identify the pharmacological behavior of a substance. Conclusion: The review finds that rasa (taste) can be used as a guide to identify potential targets in drug discovery.
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spelling doaj.art-8cc1c1180b7a431ab525d32dda83b0082022-12-22T03:09:41ZengWolters Kluwer Medknow PublicationsAncient Science of Life0257-79412014-01-0133419820210.4103/0257-7941.147419The scientific basis of rasa (taste) of a substance as a tool to explore its pharmacological behaviorSudipta Kumar RathAsit Kumar PanjaLalit NagarAshashri ShindeBackground: A rational and well-developed pharmacological basis forms the foundation of therapeutics in Ayurveda. The principles and theories of Ayurveda need to be validated in the scientific context in order to harness the millennia old knowledge. Rasa (taste) of the substance is the foremost tool in Ayurveda to assess and determine the pharmacological properties and actions of the substance. Similarity in rasa is said to signify similar structure and consequently similar pharmacological behavior. Depending on skills developed over the course of long-term clinical experience one, can register the minute variations in rasa of substances and accordingly the possible variations in pharmacological actions. Thus, rasa can be used as a scientific tool in the drug discovery process to limit and focus the target areas. Aim: To sensitize scientific community to the utility of rasa as a tool in the process of drug discovery. Materials and Methods: All relevant ancient and contemporary literature was reviewed critically to form a scientific basis of the Ayurvedic concept of rasa as a tool to identify the pharmacological behavior of a substance. Conclusion: The review finds that rasa (taste) can be used as a guide to identify potential targets in drug discovery.http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2014;volume=33;issue=4;spage=198;epage=202;aulast=RathAyurvedadrug discoverymahābhŪtarasataste
spellingShingle Sudipta Kumar Rath
Asit Kumar Panja
Lalit Nagar
Ashashri Shinde
The scientific basis of rasa (taste) of a substance as a tool to explore its pharmacological behavior
Ancient Science of Life
Ayurveda
drug discovery
mahābhŪta
rasa
taste
title The scientific basis of rasa (taste) of a substance as a tool to explore its pharmacological behavior
title_full The scientific basis of rasa (taste) of a substance as a tool to explore its pharmacological behavior
title_fullStr The scientific basis of rasa (taste) of a substance as a tool to explore its pharmacological behavior
title_full_unstemmed The scientific basis of rasa (taste) of a substance as a tool to explore its pharmacological behavior
title_short The scientific basis of rasa (taste) of a substance as a tool to explore its pharmacological behavior
title_sort scientific basis of rasa taste of a substance as a tool to explore its pharmacological behavior
topic Ayurveda
drug discovery
mahābhŪta
rasa
taste
url http://www.ancientscienceoflife.org/article.asp?issn=0257-7941;year=2014;volume=33;issue=4;spage=198;epage=202;aulast=Rath
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