Blocking MyD88 signaling with MyD88 inhibitor prevents colitis-associated colorectal cancer development by maintaining colonic microbiota homeostasis
Abstract Certain intestinal microbiota alterations appear to positively correlate with tumorigenesis of CAC due to the disruption of the balance between the host and microorganisms. It is proven that blocking MyD88 signaling can prevent colitis-associated colorectal cancer (CAC) development in mice....
主要な著者: | , , , , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
Nature Portfolio
2023-12-01
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シリーズ: | Scientific Reports |
オンライン・アクセス: | https://doi.org/10.1038/s41598-023-49457-8 |