Blocking MyD88 signaling with MyD88 inhibitor prevents colitis-associated colorectal cancer development by maintaining colonic microbiota homeostasis

Abstract Certain intestinal microbiota alterations appear to positively correlate with tumorigenesis of CAC due to the disruption of the balance between the host and microorganisms. It is proven that blocking MyD88 signaling can prevent colitis-associated colorectal cancer (CAC) development in mice....

詳細記述

書誌詳細
主要な著者: Bin Xie, Bo Wang, Runshi Shang, Lu Wang, Xia Huang, Lin Xie
フォーマット: 論文
言語:English
出版事項: Nature Portfolio 2023-12-01
シリーズ:Scientific Reports
オンライン・アクセス:https://doi.org/10.1038/s41598-023-49457-8