Association between mid-upper arm circumference and functional status in patients with advanced cancer
Summary: Background: Patients with advanced cancer suffer from various physical and psychosocial distresses. With disease progression, anorexia was also a common symptom of distress in cancer patients. Eventually, prolonged anorexia and poor nutrition leads the deterioration of patients' perfo...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-10-01
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| Series: | Clinical Nutrition Open Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667268522000432 |
| _version_ | 1811340487413465088 |
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| author | E.H. Jung Y. Hiratsuka S.-Y. Suh S.-H. Won S.-E. Choi B. Kang S.W. Lee Y.J. Kim K.J. Suh J.-W. Kim S.H. Kim J.W. Kim K.-W. Lee |
| author_facet | E.H. Jung Y. Hiratsuka S.-Y. Suh S.-H. Won S.-E. Choi B. Kang S.W. Lee Y.J. Kim K.J. Suh J.-W. Kim S.H. Kim J.W. Kim K.-W. Lee |
| author_sort | E.H. Jung |
| collection | DOAJ |
| description | Summary: Background: Patients with advanced cancer suffer from various physical and psychosocial distresses. With disease progression, anorexia was also a common symptom of distress in cancer patients. Eventually, prolonged anorexia and poor nutrition leads the deterioration of patients' performance statuses and quality of life as disease progress. Aims: This study aimed to identify direct correlations between performance status, symptom burden and mid-upper arm circumference (MUAC). Methods: This cross-sectional study was conducted with 200 patients between March 2016 and January 2019 at a tertiary cancer center in Korea. Results: A total of 65.5% of patients were on chemotherapy at enrollment, and 89.5% of the patients had a Karnofsky Performance Scale (KPS) of 70% or higher. Six items of the Korean Edmonton Symptom Assessment System (K-ESAS) (pain, fatigue, nausea, drowsiness, loss of appetite and feelings of wellbeing) showed a statistically significant negative correlation with MUAC (P<0.01) in the univariate analyses. Conversely, body mass index and KPS had a positive correlation with MUAC (P<0.01) in the univariate analyses. Finally, the KPS was significantly associated with the following three variables in the multivariate analysis: fatigue (P<0.01), feelings of wellbeing (P<0.01) in the K-ESAS and upper MUAC ≥26.5 cm group (P<0.01). Conclusion: The KPS had a significant relationship with MUAC, fatigue and feelings of wellbeing. Our study suggests that MUAC, as a simple and noninvasive tool played a vital role in functional statuses in patients with advanced cancer. |
| first_indexed | 2024-04-13T18:42:42Z |
| format | Article |
| id | doaj.art-8cc2ea4092a741ad87db0c2107300837 |
| institution | Directory Open Access Journal |
| issn | 2667-2685 |
| language | English |
| last_indexed | 2024-04-13T18:42:42Z |
| publishDate | 2022-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Nutrition Open Science |
| spelling | doaj.art-8cc2ea4092a741ad87db0c21073008372022-12-22T02:34:40ZengElsevierClinical Nutrition Open Science2667-26852022-10-01457279Association between mid-upper arm circumference and functional status in patients with advanced cancerE.H. Jung0Y. Hiratsuka1S.-Y. Suh2S.-H. Won3S.-E. Choi4B. Kang5S.W. Lee6Y.J. Kim7K.J. Suh8J.-W. Kim9S.H. Kim10J.W. Kim11K.-W. Lee12Division of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South KoreaDepartment of Palliative Medicine, Tohoku University School of Medicine, Sendai, JapanDepartment of Family Medicine, Dongguk University Ilsan Hospital, Goyang-si, South Korea; Department of Medicine, Dongguk University Medical School, Seoul, South Korea; Corresponding author. Department of Medicine, Dongguk University Medical School, Pildong 1-30, Jung-gu, Seoul, South Korea. Fax: +82 31 961-7969.Department of Family Medicine, Dongguk University Ilsan Hospital, Goyang-si, South KoreaDepartment of Statistics, Dongguk University-Seoul, Seoul, South KoreaDivision of Medical Oncology, Bundang Medical Center, CHA University, Seongnam-si, South KoreaPalliative Care Center, Yonsei Cancer Center, Yonsei University Health System, Seoul, South Korea; Division of Medical Oncology, Yonsei Cancer Center, Yonsei University Health System, Seoul, South KoreaDivision of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South KoreaDivision of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South KoreaDivision of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South KoreaDivision of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South KoreaDivision of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South KoreaDivision of Hematology and Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South KoreaSummary: Background: Patients with advanced cancer suffer from various physical and psychosocial distresses. With disease progression, anorexia was also a common symptom of distress in cancer patients. Eventually, prolonged anorexia and poor nutrition leads the deterioration of patients' performance statuses and quality of life as disease progress. Aims: This study aimed to identify direct correlations between performance status, symptom burden and mid-upper arm circumference (MUAC). Methods: This cross-sectional study was conducted with 200 patients between March 2016 and January 2019 at a tertiary cancer center in Korea. Results: A total of 65.5% of patients were on chemotherapy at enrollment, and 89.5% of the patients had a Karnofsky Performance Scale (KPS) of 70% or higher. Six items of the Korean Edmonton Symptom Assessment System (K-ESAS) (pain, fatigue, nausea, drowsiness, loss of appetite and feelings of wellbeing) showed a statistically significant negative correlation with MUAC (P<0.01) in the univariate analyses. Conversely, body mass index and KPS had a positive correlation with MUAC (P<0.01) in the univariate analyses. Finally, the KPS was significantly associated with the following three variables in the multivariate analysis: fatigue (P<0.01), feelings of wellbeing (P<0.01) in the K-ESAS and upper MUAC ≥26.5 cm group (P<0.01). Conclusion: The KPS had a significant relationship with MUAC, fatigue and feelings of wellbeing. Our study suggests that MUAC, as a simple and noninvasive tool played a vital role in functional statuses in patients with advanced cancer.http://www.sciencedirect.com/science/article/pii/S2667268522000432Mid-upper arm circumferenceCancer symptomsKarnofsky performance scaleFunctional status |
| spellingShingle | E.H. Jung Y. Hiratsuka S.-Y. Suh S.-H. Won S.-E. Choi B. Kang S.W. Lee Y.J. Kim K.J. Suh J.-W. Kim S.H. Kim J.W. Kim K.-W. Lee Association between mid-upper arm circumference and functional status in patients with advanced cancer Clinical Nutrition Open Science Mid-upper arm circumference Cancer symptoms Karnofsky performance scale Functional status |
| title | Association between mid-upper arm circumference and functional status in patients with advanced cancer |
| title_full | Association between mid-upper arm circumference and functional status in patients with advanced cancer |
| title_fullStr | Association between mid-upper arm circumference and functional status in patients with advanced cancer |
| title_full_unstemmed | Association between mid-upper arm circumference and functional status in patients with advanced cancer |
| title_short | Association between mid-upper arm circumference and functional status in patients with advanced cancer |
| title_sort | association between mid upper arm circumference and functional status in patients with advanced cancer |
| topic | Mid-upper arm circumference Cancer symptoms Karnofsky performance scale Functional status |
| url | http://www.sciencedirect.com/science/article/pii/S2667268522000432 |
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