4353 The Role of BCL2 Mediated Calcium Signaling on Leukemia Stem Cell Metabolism

4353 The Role of BCL2 Mediated Calcium Signaling on Leukemia Stem Cell Metabolism

OBJECTIVES/GOALS: The objective of this study is to define the molecular mechanisms that control survival of malignant stem cells in acute myeloid leukemia (AML). Leukemia stem cells (LSCs) are not effectively eradicated by standard treatment and lead to resistance and relapse, which contribute to p...

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Bibliographic Details
Main Authors:	Anagha Inguva, Shanshan Pei, Maria Amaya, Brett Stevens, Courtney Jones, Daniel Pollyea, Craig Jordan
Format:	Article
Language:	English
Published:	Cambridge University Press 2020-06-01
Series:	Journal of Clinical and Translational Science
Online Access:	https://www.cambridge.org/core/product/identifier/S2059866120000989/type/journal_article

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