Type 2 cytokines promote angiogenesis in ischemic muscle via endothelial IL-4Rα signaling

Type 2 cytokines promote angiogenesis in ischemic muscle via endothelial IL-4Rα signaling

Summary: Peripheral arterial disease (PAD) is one of the leading causes of cardiovascular morbidity and mortality worldwide, yet current trials on therapeutic angiogenesis remain suboptimal. Type 2 immunity is critical for post-ischemic regeneration, but its regulatory role in revascularization is p...

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Bibliographic Details
Main Authors: Huixian Li, Chufeng He, Ruiwen Zhu, Francis M. Chen, Lin Wang, Fung Ping Leung, Xiao Yu Tian, Gary Tse, Wing Tak Wong
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Cell Reports
Subjects:
CP: Metabolism
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723009750

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