Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile

Objective. Estimate baseline coagulation profile values in patients scheduled for cardiosurgical intervention in age groups of pediatric population.Material and Methods. The coagulation profile was analyzed in a complete selection of patients admitted to the intensive care department of Scientific R...

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Main Authors: N. B. Karakhalis, A. Kh. Kade, A. V. Bratova
Format: Article
Language:Russian
Published: Scientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1 2020-03-01
Series:Инновационная медицина Кубани
Subjects:
Online Access:https://www.innovmedkub.ru/jour/article/view/243
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author N. B. Karakhalis
A. Kh. Kade
A. V. Bratova
author_facet N. B. Karakhalis
A. Kh. Kade
A. V. Bratova
author_sort N. B. Karakhalis
collection DOAJ
description Objective. Estimate baseline coagulation profile values in patients scheduled for cardiosurgical intervention in age groups of pediatric population.Material and Methods. The coagulation profile was analyzed in a complete selection of patients admitted to the intensive care department of Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1 for the period from January to December 2018. The study includes 842 patients planned for cardiac surgery.Results. This study demonstrates the dependence of the basic parameters of the hemostasis system on age characteristics, mainly during the period of the first year of life. APPT values were similar in all age groups, whereas extended PV was recorded in patients less than one year.Conclusion. Evaluation of coagulation system parameters should be based on age-specific reference values. Understanding the concept of developing hemostasis is extremely important in conditions of optimal prevention, diagnosis and treatment of hemorrhagic and thrombotic conditions in the pediatric population.
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spelling doaj.art-8cc610f593914dc0bd157a1f8861539d2024-03-05T11:12:30ZrusScientific Research Institute, Ochapovsky Regional Clinical Hospital no. 1Инновационная медицина Кубани2541-98972020-03-0101232910.35401/2500-0268-2020-17-1-23-29218Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profileN. B. Karakhalis0A. Kh. Kade1A. V. Bratova2Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1; Kuban State Medical UniversityKuban State Medical UniversityScientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1Objective. Estimate baseline coagulation profile values in patients scheduled for cardiosurgical intervention in age groups of pediatric population.Material and Methods. The coagulation profile was analyzed in a complete selection of patients admitted to the intensive care department of Scientific Research Institute – Ochapovsky Regional Clinical Hospital no. 1 for the period from January to December 2018. The study includes 842 patients planned for cardiac surgery.Results. This study demonstrates the dependence of the basic parameters of the hemostasis system on age characteristics, mainly during the period of the first year of life. APPT values were similar in all age groups, whereas extended PV was recorded in patients less than one year.Conclusion. Evaluation of coagulation system parameters should be based on age-specific reference values. Understanding the concept of developing hemostasis is extremely important in conditions of optimal prevention, diagnosis and treatment of hemorrhagic and thrombotic conditions in the pediatric population.https://www.innovmedkub.ru/jour/article/view/243coagulationchildhood agedeveloping hemostasisreference values
spellingShingle N. B. Karakhalis
A. Kh. Kade
A. V. Bratova
Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile
Инновационная медицина Кубани
coagulation
childhood age
developing hemostasis
reference values
title Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile
title_full Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile
title_fullStr Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile
title_full_unstemmed Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile
title_short Age-dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile
title_sort age dependent changes of coagulation system parameters in pediatric patients of cardiosurgical profile
topic coagulation
childhood age
developing hemostasis
reference values
url https://www.innovmedkub.ru/jour/article/view/243
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